Zofran

Question 1

Name for ondanestron

Answer 1

Zofran

Question 2

Class for ondanestron

Answer 2

Antiemetic, antagonist, selective serotonin receptor

Question 3

Indication for ondanestron

Answer 3

Prevention and control of nausea or vomiting

Question 4

MOA for ondanestron

Answer 4

blocks the action of serotonin, a natural substance that causes nausea andvomiting

Question 5

Side effects for ondanestron

Answer 5

headache, malaise, syncope, wheezing dysrhythmias, palpitations

Question 6

Dose for ondanestron

Answer 6

Ped - 6 months to 14 years - 0.15 mg/kg IV or orally, maximum 4 mg
Adult 4 mg IV / SL

Question 7

Special consideration for ondanestron

Answer 7

B

Question 8

Drug interaction for ondanestron

Answer 8

Avoid drugs that prolong the QT interval - fentanyl, amioderone

Question 9

Duration for ondanestron

Answer 9

onset 30 mins
peak 1.3 hrs oral/ 10 mins IV
duration 3 to 6 hrs

Question 10

Contraindications for Ondanestron

Answer 10

Hypersensitivity, suspected long QT syndrome