#28 Flashcards

(54 cards)

1
Q

Venules

A

smallest type of veins that connect to capillary beds and lack a tunica media

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2
Q

Tunica media

A

middle, typically thickest layer of blood vessel walls

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3
Q

Arteries

A

thick-walled muscular vessels that carry oxygen-rich blood away from the heart at high pressure

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4
Q

Arterioles

A

small arteries, regulate blood flow into capillary beds and influence blood pressure through constrictrion or dilation

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5
Q

Organize aorta and varients from biggest to smallest

A

Aorta -> large arteries -> medium/small arteries -> arterioles

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6
Q

Inferior vena cava

A

largest vein responsible for transporting deoxygenated blood from the lower body back to the heart

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7
Q

Veins

A

large vessels that carry blood back towards the heart

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8
Q

Elastic arteries

A

near the heart, alrge and thick-walled and contains high amounts of elastic tissue to handle high-pressure surges from the heart

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9
Q

Muscular arteries

A

medium-sized vessels with more smooth muscle, distributing blood to specific organs

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10
Q

Tunica intima

A

inner layer composed of smooth

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11
Q

Blood pressure gradient

A

The difference in pressure between two points in the cardiovascular system

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12
Q

Vascular resistance

A

Opposition to blood flow within the cardiovascular system

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13
Q

What determins vascular resistance?

A

blood vessel diameter, vessel length, blood viscosity

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14
Q

Blood flow rate

A

The volume of blood passing a point per unit of time

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15
Q

Blood viscosity

A

the thickness and stickiness of blood measuring its resistance to flow within vessels

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16
Q

How does blood move?

A

from high to low pressure

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17
Q

What is the relationship between vessel resistance and length?

A

The longer the vessel, the more surface that is in contact with the blood and thus more friction blood will encounter. increases linearly with length

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18
Q

Four factors that can affect vascular resistance

A

length, diameter, viscosity and turbulence

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19
Q

Turbulence

A

Disruption to blood flow that increases resistance. Occurs at high flow rates or in damaged vessels

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20
Q

What does blood vessel smooth msucle respond to?

A

ANS, sympathetic innervation, and to a variety of different hormones

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21
Q

What effect does vessel diameter have on resistance?

A

A change in diameter of a vessel produces a larger change than change in length, resistance is proportional to the radius

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22
Q

What happens when a liquid is more viscous?

A

Molecules and materials suspended within it interact with each other causing internal friction which slows down overall flow

23
Q

Laminar flow

A

all the liquid is moving in one direction in smooth layers

24
Q

Turbulent flow

A

layers are disrupted and the movement is not all unidirectional so overall flow is reduced for a given pressure gradient

25
What in vessel walls can cause turbulent flow
branch points tight curves irregular surfaces
26
How does vessel length relate to resistance?
longer vessels increase resistance, shorter vessels decrease resistance
27
How is vessel diameter related ot resistance?
A smaller diameter would drastically increase resistance, a wider diameter would reduce it
28
Korotkoff sounds
caused by the turbulent high-velocity flow of blood through the partially compressed brachial artery in a blood pressure test
29
How does arterial pressure fluctuate due to cardiac cycle?
Highest during and just after ventricular systole and lowest during diastol
30
Pulse pressure
difference between systolic and diastolic pressure, force heart generates with each contraction
31
Mean arterial pressure
diastolic pressure + 1/3 pulse pressure
32
What do elastic arteries do for pulse pressure?
helps to buffer and reduce variability in blood flow and pressures in capillaries
33
What happens with arteries with large amounts of elastic tissue?
stretches when blood is forced into them with high pressure temporarily reducing blood flow rate
34
How is blood pressure measured?
sphygomanometer which tracks how much external pressure it takes to stop blood flow
35
What does the cuff do in a blood pressure test?
Tightens to a pressure that is higher than systolic blood pressure
36
Systolic blood pressure
maximum pressure in your arteries when the heart contracts and pumps blood
37
diastolic pressure
pressure in the arteries when the heart rests between beats
38
Why must the cuff compress the artery to temporarily stop blood flow?
To measure when the blood starts moving again and when it flows freely
39
40
First sound of blood pressure measurement
this is the peak pressure of the heart contraction
41
What are the continuing sounds when measuring blood pressure?
the sounds continue after the first, changing quality and then disappear which signifies diastolic pressure
42
What happens to blood pressure as it passes throug hthe systemic circuit?
it declines as it encounters a series of resistances
43
Where is the source of pressure gradient and what happens further away?
source is the ventricle, the further vessels are away from it the lower the average pressure is within them
44
Where is the pressure drop-ff the largest?
through the arterioles, these vessels provide the highest total resistance to volume flow
45
How can gravity affect blood flow?
Can either oppose or enhance, according to the location of vessels relative to the heart
46
What must arteries work against?
Working to generate enough pressure to pus hagainst the force of gravity as well as vascular resistance
47
What does gravity assist in blood flow?
When arteries supply blood to regions blow he heart
48
What do veins in limbs contain?
valves to prevent the backflow of blood due to gravity
49
How dies blood get squeezed upwards towards the heart?
muscles contracting around the vein provide extra pressure which helps squeeze blood upward toward the heart, countering the force of gravity
50
Concentric hypertrophy
results from pressure overload. creates increases in ventricular wall thickness
51
Eccentric hypertrophy
results from volume overload, creates increased ventricular volume
52
What do concentric and eccentric hypertrophy represent?
distinct remodelling patterns of the ventricular myocardium in response to hemodynamic stress
53
Features of concentric hypertrohpy
- cardiomyocytes increase in width (parallel addition of sarcomeres) - thick walls and a reduced cavity radius - diastolic dysfunction leading to lower myocardial efficiency
54
features of eccentric hypertrophy
- cardiomyocytes elongate (serial addition of sarcomeres) - chamber dilation and thinner/normal wall thickness - maintains or increases stroke volume initially but leads to systolic dysfunction as dilation becomes excessive