What is the urine system responsible for?
production, stoage and elimination of urine
What do the kidneys do?
filter blood, producing urine
Where is urine moved and stored
throughout the urinary system and temporarily stored in the bladder
Parts of the urinary tract
Kidneys, Ureters, Urinary Bladder, Urethra
What does micturition [urination] rely on?
coordination of bladder and urethral sphincter muscles through the autonomic and somatic nervous systems
What must happen for the bladder to empty?
Urgency
describes the desire to urinate
Frequency
describes the rate of urination [how many times]
Incontinence
describes the lack of [voluntary] control preventing urination
Retention
describes when urination does not occur
Kidneys have many functions, mostly revolving around body fluid homeostasis. What do they remove and regulate?
Removes wastes and toxins from blood without removing nutrients
Regulating plasma ion concentrations, blood pH, blood volume and pressure
The kidney is both a secondary ___ organ and a ____ of other of these types of organs
endocrine, target
Calcitriol
regulates calcium intake and retention
When is cacitriol secreted
in response to parathyroid hormon PTH signalling when calcium is low
How does calcitriol act?
through receptors in digestive tract and kidney to promote absorption and reabsorption of calcium
Erythropeoietin [EPO]
Stimulates red blood cell production
When is EPO secreted?
secreted by intertubular fibroblasts [EPCs] within kidney tissue in response to tissue hypoxia [lack of oxygen]
What does EPO act on?
bone marrow to enhance RBC production leading to increases in blood volume
Renin
regulates other hormones which control blood pressure and plasma volume
When is renin secreted?
within the juxtaglomerular apparatus [JGA] in response to decreased pressure in kidney arterioles
What does Renin activate?
RAAS, leading to increased blood pressure through vasoconstriction and increased blood voume through intake and reabsorption
Nephron
functional unit of kidney tissue
What does each nephron have?
A glomerulus where blood is initially filtered
A renal tubule where filtrate is processed
Glomeruli
capillaries in kidneys