What is potency?
The ability of stem cells to undergo differentiation
Totipotent
Able to divide into any type of cell (including the extraembryonic cells)
Pluripotent
Able to divide into any type of cell except the extraembryonic cells
Multipotent
Able to divide into a handful of different cell types
Unipotent & example
Able to divide into one type of cell
Cardiomyocites
Where are pluripotent cells found?
Embryos
Where are totipotent cells found?
Limited time in early mammalian
embryos
Where are multipotent and unipotent cells found?
Mature animals bone marrow
How are stem cells used in medicine
Stem cell transplants
Research
Growing organs
How are iPS cells produced
Taking adult stem cells and reprogramming them into a pluripotent stem cell by a cocktail of transciption factor.
How are iPS cells enter the body
Packaged them inside a virus and infect adult cells
Advantages of iPS cells
Do not have ethical baggage
Genetically identical to the patient so reduce the risk of rejection