Threshold value meaning and voltage
Minimum level of stimulus needed to trigger an action potential
-55 mV
Mechanisms behind resting potential
ATP used so 3 Na+ ions move out and 2 K+ ions move in to the cell membrane.
Na+ ion channels close so they cannot diffuse back into the cell (impermeable membrane).
K+ ion channels open so facilitated diffusion out of neurone to concentration gradient.
Net movement out of cell then inside cell.
Process of a generator potential
Stimulus detected.
Membrane becomes more permeable to Na+.
Causes change in voltage of membrane so the membrane is depolarised.
Bigger stimulus = more Na+ ion movement = larger change in voltage.
If voltage crosses a certain threshold, action potential occurs.
Increasingly postive inside the cell.
Action potential process
Once threshold reached, more Na+ ions channels open.
More Na+ ions enter cell which makes it more positive then outside the cell.
Frequency of action potential increases strength of stimulus.
Process of repolarisation
Na+ ion chanels close, K+ ion channels open.
More K+ ions diffuse out of the cell down the gradient which creates requirements of resting potential (more negative inside the cell).
Where are negative organic ions found? Why is this important?
Found in axon
Cause of negative charge in axon
Voltage of resting potential?
-65 - -70 mV
What is the ‘all or nothing’ principle
The action potential is the same size regardless of how much it is over the threshold.
Voltage of the action potential?
40 mV
Properties of resting potential
Receptor is not being stimulated.
Inside of cell more negative then outside the cell.
Voltage across the membrane.
Membrane is polarised.
Structure and function of a motor neurone
Cell body - Contains organelles where proteins & neurotransmitters are produces
Dendrites - Carry action potential to surrounding cells
Axon - Carries nervous impulse along the motor neurone
What is the cells (+ function) and gaps involved in myelinated motor neurones
Schwann cells
Wrap the axon to form the myelin sheath which is a lipid and disallows charged ions to pass through.
Gaps = nodes of Ranvier
What is saltatory conduction
Action potentials jumps from node to node so are transferred quicker
Temperature effect on rate of nerve impulses
Higher temp = faster rate
Faster ion diffusion
Enzymes in respiration work faster so more ATP for active transport in pumps
Axon diameter effect on rate of nerve impulses
Wider diameter = faster rate
Speed of conduction increases as there is less resistance to the ion flow
What is the refractory period and its effect?
Mass movement of positive ions out of the membrane makes it more negative then -70 mV.
Limits action potentials fired as many Na+ ions needed.
Discreet impulses produced which are not continously stimulated and seperate.