Function and structure of smooth muscle
Unstriated
Spindle shaped cells
Uninucleated
Control artery contractions and processes such as peristalsis
Function and structure of skeletal muscle
Striated
Cylindrical cells
Multinucleated
Lots of mitochondria
Move bones via contraction
Function and structure of cardiac muscle
Striated
Branched cells
Uninucleated
Intercalated
Pump blood around the heart
What is a myofibril a repeating unit of
Sarcomeres
Make up of skeletal muscle
Muscle cells -> muscle fibres -> skeletal muscle
Cytoplasm and cell membrane in a skeletal muscle
Sarcoplasm, sarcolemma
Adaptation of sarcolemma
Contain foldings of T tubules which help spread electrical impulses quickly
What are the 2 bundles within myofibrils and thickness
Myosin - Thick
Actin - Thin
What is A band
Dark bands where actin and myosin overlap
What is I band
Light band of just actin
What is Z line
Centre of an I band which has a sarcomere inbetween
What is H zone
Myosin filament with no actin overlap
How does myofibril change during contraction
H zone and I band shortens as actin is pulled over myosin
A band remains the same length as myosin filament doesn’t shorten
Z lines get closer together because the sarcomere gets shorter
What band and colour is actin and myosin within a sarcomere?
Actin - I & Light
Myosin - H & Dark
Properties of slow twitch muscle fibres
Darker in colour due to higher concentrations of myoglobin
Contract slower
Slower to fatigue
Energy released slowly from aerobic respiration
Lots of mitochondria for ATP and blood vessels to reduce gas diffusion pathways
Properties of fast twitch muscle fibres
Lighter in colour due to lower concentrations of myoglobin
Contains lots of glycogen to be broken down into glucose - this helps in the high rate of anaerobic respiration
Contract quickly
Fatigue quickly
Energy released quickly from anaerobic respiration
Few mitochondria and blood vessels
Structure of myosin filaments
Globular heads hinged so can move with the addition of ATP
Each head has a binding for actin and ATP
Structure of actin filaments
Has binding sites for myosin heads called actin-myosin
Tropomyosin are long chains which coil around actin filaments
Why do both slow and fast muscle fibre contain ATPase? [2]
[1] Hydrolysis of ATP;
[2] (Muscle) contraction requires energy / ATP;
What is ATPase two different functions in slow and fast twitch fibres?
Fast - (lots of) ATPase allows rapid hydrolysis of ATP
Slow - (lots of) ATPase allows rapid synthesis of ATP.