Aminoglycosides

Question 1

Aminoglycosides Drawback

Answer 1

nephrotoxicity and ototoxicity
Also and for corneas in eye infections

Question 2

Aminoglycosides Distribution

Answer 2

poorly absorbed from GI tract, parenteral administration is necessary to treat systemic infections; they are weakly bound to serum proteins (10%) and freely distribute into the extracellular fluid.

Question 3

Aminoglycosides Clinical uses

Answer 3

primarily used in treating gram-negative infections, including neutropenic fever and nosocomial infections.