Streptogramins

Question 1

the only streptogramin antibiotic available in the United States.

Answer 1

Quinupristin/dalfopristin (Synercid)

Question 2

Streptogramins Distribution

Answer 2

not absorbed from the GI tract; IV administration, moderately protein bound

Question 3

Streptogramins Half life

Answer 3

1 hour

Question 4

Streptogramins Elimination

Answer 4

metabolism is through liver; excreted in feces.

Question 5

Streptogramins Clinical uses

Answer 5

treating skin and skin structure infections and vancomycin-resistant E. faecium infections.

Question 6

Streptogramins Adverse events (think how it metabolizes)

Answer 6

infusion-related reactions; increased conjugated bilirubin.