Carbapenems

Question 1

Carbapenems Description

Answer 1

Bicyclical beta-lactams with a common carbapenem nucleus; most broad-spectrum agents available.

Question 2

Carbapenem Distribution

Answer 2

widely distributed into most tissues, are minimally bound to plasma proteins

Question 3

Carbapenems Half life

Answer 3

1 hour

Question 4

Carbapenems Elimination

Answer 4

are primarily eliminated by urinary excretion

Question 5

Carbapenems Mechanism of Action

Answer 5

bind to the PBPs on cell wall and interfere with bacterial cell wall synthesis.

Question 6

Carbapenems Clinical Uses

Answer 6

treating polymicrobial infections

Question 7

Carbapenems Side effects

Answer 7

neurotoxicity GI side effects reported.