Macrolides

Question 1

Macrolides Example

Answer 1

Erythromycin (E-Mycin), the prototypical macrolide, has been used in treating many infections over the years. However, its use has been diminished by GI side effects.

Question 2

Macrolides Distribution

Answer 2

oral; are absorbed from the GI tract; have good tissue penetration, high intracellular concentration, and minimal protein binding

Question 3

Macrolides Elimination

Answer 3

Metabolized by the liver

Question 4

Macrolides Clinical uses

Answer 4

treating respiratory tract, skin, and soft-tissue infections; sexually transmitted diseases; HIV-related Mycobacterium avium–intracellulare complex infection; and other infections caused by atypical organisms.