neuron comprised of
axon dendrites soma myelin sheath axon terminals
dendrites
receive information from other neurons
- carry from synapse to soma
soma
cell body which controls metabolism and maintenance of neuron
- receives messages from other neurons
axon
nerve fibre that extends from soma and carries information towards the cells the communicate with that neuron
myelin sheath
axon terminals
found at the end of axon branch and transmit messages to the next neuron
neurotransmitters
chemicals that transmit information from one neuron to the next via synapse
- are contained in synaptic vesicles within the terminal button of the neuron’s axon terminal
synaptic transmission
process of neurons transmitting information between each other
lock and key process
when a pre-synapatic neuron fires, synaptic vesicles move towards the pre-synaptic membrane, fuses with it and releases the neurotransmitters into the synaptic cleft.
excitory
releases a neurotransmitter that ‘excites’ the post synaptic neuron or causes it to reach its action potential
inhibitory
firing rate of post-synaptic neuron is reduced
firing speed is dependent on
synaptic activity
how active soma is
glutamate
excites every neuron in brain and rest of nrvous system
- important role in learning and memory
GABA
inhibitory effect
- important role in regulating anxiety
dementia
decrease in concentration of acetylcholine in cns
- severe memory loss and disorientation
parkinson’s disease
progressive neurological condition caused by degeneration of dopamine-releasing neurons in substantia nigra
substantia nigra
part of basal ganglia
(midbrain)
- responsible for reward, addiction and Parkinson’s disease (coordination of movement)
- where there are dopamine-releasing neurons
dopamine
neurotransmitter that helps control the brain;s rewards and pleasure centres (including basal ganglia)
absence of dopamine
neurons in striatum fire uncontrollably and Parkinson’s sufferer unable to control their movement adequately
symptoms
slowness of movement, reduced facial expressions, difficulty sleeping
for effective motor functioning
striatum must have balance of dopamine and acetylcholine levels
treatment
drugs