Dabigatran

Question 1

What is dabigatran?

Answer 1

oral anticoagulant

Question 2

What does dabigatran directly inhibit?

Answer 2

thrombin

Question 3

What is dabigatran used in?

Answer 3

• prophylaxis of venous thromboembolism following hip or knee replacement surgery
• prevention of stroke in patients who have non-valvular a fib with 1 or more risk factors

Question 4

What is a major side effect of dabigatran?

Answer 4

haemorrhage

Question 5

What drug can be used for rapid reversal of the anticoagulant effects of dabigatran?

Answer 5

idarucizumab