Loop diuretics

Question 1

What is an example of a loop diuretic?

Answer 1

furosemide

Question 2

What do loop diuretics inhibit and what is the result?

Answer 2

Na-K-Cl transporter (NKCC)
- reduces absorption of NaCl

Question 3

What are loop diuretics used in?

Answer 3

• HF = acute (IV) and chronic (oral)
• resistant hypertension

Question 4

What are the side effects of loop diuretics?

Answer 4

• hypotension
• hypokalaemia
• hypocalcaemia
• ototoxicity
• renal impairment
• gout