Diltiazem

Question 1

Diltiazem Trade Name?

Answer 1

Cardizem

Question 2

Diltiazem Classification?

Answer 2

Class IV Antidysrhythmic; Calcium Channel Blocker

Question 3

Diltiazem Mechanism?

Answer 3

Inhibits extracellular calcium ion influx across membranes of myocardial cells and vascular smooth muscle cells with substantial inhibitory effects on cardiac conduction system, acting principally at AV node, with some effects at sinus node

Question 4

Diltiazem Indications?

Answer 4

• Atrial fibrillation and atrial flutter with rapid ventricular response
• SVT refractory to adenosine

Question 5

Diltiazem Contraindications?

Answer 5

• Heart Blocks
• Hypotension
• Decompensated Cardiogenic Shock
• Ventricular Tachycardia
• WPW Syndrome

Question 6

Diltiazem Side Effects/Precautions?

Answer 6

• Syncope
• Nausea/Vomiting
• AV blocks
• Bradycardia
• Hypotension
• Chest pain
• VF/VT
• CHF

Question 7

Diltiazem Adult Dose?

Answer 7

• 10mg IV/IO over 2 min repeat every 10 min.
• Maintenance infusion: 5-15 mg/hr titrated to heart rate

Question 8

Diltiazem Pediatric Dose?

Answer 8

Not Recommended

Question 9

Diltiazem Onset of Action?

Answer 9

2-5 Minutes

Question 10

Diltiazem Duration of Action?

Answer 10

1-3 Hours

Question 11

Diltiazem Max Dose Adult/Pediatric?

Answer 11

20 mg/dose. N/A for Peds

Question 12

Diltiazem Routes of Administration?

Answer 12

IV/IO

Question 13

Diltiazem How Supplied?

Answer 13

25mg/5ml vials