Norepinepherine

Question 1

Norepinephrine Trade Name?

Answer 1

Levophed

Question 2

Norepinephrine Classification?

Answer 2

Sympathomimetic

Question 3

Norepinephrine Mechanism?

Answer 3

Binds to A1, and B1 adrenergic receptors with more profound A1 effects to cause peripheral vasoconstriction and coronary vasodilation. Primary action is with calcium channels

Question 4

Norepinephrine Indications?

Answer 4

• Cardiogenic shock
• Septic shock following fluid resuscitation
• Neurogenic shock

Question 5

Norepinephrine Contraindications?

Answer 5

-Hypovolemia
-Tachydysrhythmias

Question 6

Norepinephrine Side Effects/Precautions?

Answer 6

• Tachycardia
• Hypertension
• Increased myocardial oxygen demand
• Dysrhythmia
• Headache
• Nausea/vomiting
• Syncope

Question 7

Norepinephrine Adult Dose?

Answer 7

1 - 30 mcg/min IV/IO infusion

Question 8

Norepinephrine Pediatric Dose?

Answer 8

0.01 - 2.0 mcg/kg/min IV/IO infusion

Question 9

Norepinephrine Onset of Action?

Answer 9

1-3 Minutes

Question 10

Norepinephrine Duration of Action?

Answer 10

Variable. Lasts about 1 minute after infusion stops.

Question 11

Norepinephrine Max Dose Adult/Pediatric?

Answer 11

Adults: No located in EMS application
Peds: 1-2mcg/kg/min

Question 12

Norepinephrine Routes of Administration?

Answer 12

IV/IO

Question 13

Norepinephrine How Supplied?

Answer 13

• 4mg vials
• Mix 4mg in 250ml NS for a concentration of 16 mcg/ml