what is the spectrum of activity of tetracyclines
broad
are tetracyclines bacteriocidal or bacteriostatic
bacteriostatic works by binding to 30s ribosomes
what are some different indications for tetracyclines
acne
pnuemonia
chlamydia
cellulitis
diabetic foot
rickettsia infections
mrsa infections
animal bites
can tetracyclines treat infections with atypical bacteria?
yes
what tetracycline is different to the rest and why
minocycline
greater spectrum of activity
^ risk of lupus like syndrome
^ risk of irrevsible pigmentation
what condition is muscle weakness prevalent in while someone takes tetracyclines
myasthenia gravis
what advice should we give to patient
discontinue if headache or visual change
take with food or while standing and avoid milky liquids or antacids two hours before and two hours after taking the dose.
can cause sunlight sensitivity
can doxycycline be used in pregnancy or breastfeeding?
no