Week 3

Question 1

Which of the following interacts with clarithromycin

donepezil
galantamine
rivastigmine
memantine

Answer 1

Galantamine

Question 2

Which of the following interacts with carbamazepine and the three Ps of epilepsy

donepezil
galantamine
rivastigmine
memantine

Answer 2

donepezil

Question 3

Which of the following is preferred for the management of mild to moderate alzheimers first line

donepezil
galantamine
rivastigmine
memantine

Answer 3

donepezil as it is vastly cheaper than other the other medications

Question 4

Which of the following is not a metaboliser of donepezil

cyp450
2d6
3a4
4d5

Answer 4

4d5

Question 5

which of the following is not a drug that interacts with donepezil

amiodarone
citalopram
clarithromycin
betablockers
calcium channel blockers
amiodarone

Answer 5

calcium channel blockers

Question 6

If a patient is using a weekly rivastigmine patch which of the following is the amount of time before an area can be used again

7 days
14 days
21 days
28 days
30 days

Answer 6

14 days

Question 7

Which of the following is correct

Donepezil is affected by food
Rivastigmine is affected by food when taken orally
Rivastigmine is affected by food when applied transdermally
Galantamine isn’t affected by food when taken orally

Answer 7

Rivastigmine is affected by food when taken orally

it is potent!!! so more gi side effects

Question 8

Remember no Rivastigmine should be smoking since increases the exposure

Answer 8

Remember no Rivastigmine should be smoking since increases the exposure

Question 9

Which of the following drugs acts as a nictotinic receptor agonist

donepezil
rivastigmine
galantamine
memantine

Answer 9

galantamine

Question 10

which of the following drugs are contraindicated in severe hepatic and renal impairment

donepezil
galantamine
rivastigmine
memantine

Answer 10

Galantamine

Question 11

Which of the following drugs can cause neuroleptic malignancy

donepezil
galantamine
rivastigmine
memantine

Answer 11

donepezil

Question 12

Which of the following drugs can cause steven johnson syndrome

donepezil
galantamine
rivastigmine
memantine

Answer 12

galantamine

Question 13

What is the acronym to remember the aminoglycosides

Answer 13

GANST

Question 14

name 5 aminoglycosides

Answer 14

Gentamycin
Amikacin
Neomycin
Streptomycin
Tobramycin

Question 15

Which of the following is not a indication of aminoglycoside

Pnuemonia
Meningitis
Septiceamia
Endocarditis
Otitis media

Answer 15

otitis media

Question 16

Name the four main indications for aminoglycosides

Answer 16

pnuemonia
meningitis
septiceamia
endocarditis

Question 17

Describe the bacterial coverage of a typical aminoglycoside

Answer 17

has more coverage against gram -ve and works against psuedomonas arueginosa does not work as well against gram +ve but does affect staph aureas and mrsa

Question 18

Name the different side effects of a typical aminoglycoside

Answer 18

Nueromuscular transmission
Peripheral Nueropathy
Ototoxicity
Nephrotoxicity
Antibiotic associated collitis
Electrolyte imbalance

Question 19

Which of the following is not a side effect of a typical aminoglycoside

Nueromuscular transmission
Peripheral Nueropathy
Ototoxicity
Nephrotoxicity
Hepatotoxicity

Answer 19

Hepatotoxicity

Question 20

Which of the following is not a typical kind of electrolyte imbalance associated with typical aminoglycosides

hypokalemia
hypomagnesemia
hyponatraemia
hypocalcemia

Answer 20

hyponatraemia

Question 21

What are the main cautions for aminoglycosides

Answer 21

Myasthenia gravis (long term muscle wastage)

Use of other ototoxic or nephrotoxic drugs

Question 22

Which of the following aminoglycosides can be used for bowel sterilization

gentamycin
amikacin
neomycin
streptomycin
tobramycin

Answer 22

neomycin can be given orally to sterilize the bowels