Endocrine Flashcards

(31 cards)

1
Q

What are the symptoms the patient is experiencing that suggest type 2 diabetes mellitus?

A
  • Fatigue
  • Excessive thirst
  • Excessive hunger

These symptoms are common indicators of diabetes.

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2
Q

What is the threshold for a fasting plasma glucose level to indicate diabetes?

A

> 126 mg/dL

A fasting plasma glucose level above this value suggests diabetes.

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3
Q

What is the threshold for a random plasma glucose level to indicate diabetes?

A

> 200 mg/dL

A random plasma glucose level above this value confirms diabetes.

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4
Q

What is the threshold for an oral glucose tolerance test to indicate diabetes?

A

> 200 mg/dL (2-hour blood glucose level)

This result is obtained after a 75-g glucose load.

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5
Q

What is the normal range for glycated hemoglobin (A1C) levels?

A

<6%

A level below this indicates normal glucose control.

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6
Q

What is the first-line test for patients with a high risk of suspicion for pheochromocytoma?

A

Measure plasma fractionated metanephrines

High risk includes patients with an adrenal mass on CT, family history, genetic syndromes, or history of resected pheochromocytoma.

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7
Q

What are the classic symptoms of pheochromocytoma?

A
  • Episodic headache
  • Sweating
  • Tachycardia

These symptoms are concerning for pheochromocytoma and may indicate the need for further testing.

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8
Q

Best initial screening test for both hypothyroidism and hyperthyroid diesel

A

TSH

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9
Q

Hypothyroidism

A

Elevated TSH and decrease T3 T4

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10
Q

Hyperthyroidism

A

Decrease TSH and elevated T43 T4

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11
Q

What are the ocular effects more specific to hypertension?

A
  • AV nicking
  • Retinal arterial narrowing
  • Papilledema

These effects are distinct from those seen in diabetic retinopathy.

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12
Q

What is the hemoglobin A1C level that indicates prediabetes?

A

5.7% to <6.5%

A hemoglobin A1C level of 5.9% is indicative of prediabetes.

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13
Q

What fasting blood glucose range is considered prediabetes?

A

100 to 125 mg/dL

A fasting plasma glucose of ≥126 mg/dL is diagnostic for diabetes.

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14
Q

What is the 2-hour plasma glucose value range during a 75-g oral glucose tolerance test that indicates prediabetes?

A

140 to 199 mg/dL

A value of ≥200 mg/dL is diagnostic for diabetes.

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15
Q

What fasting plasma glucose level is diagnostic for diabetes?

A

≥126 mg/dL

This level indicates that the individual has diabetes.

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16
Q

What does metabolic syndrome refer to?

A

A cluster of high risk symptoms that can increase your risk of heart disease, stroke, and diabetes

Metabolic syndrome is characterized by the presence of three or more specific risk factors.

17
Q

What does the letter P in the mnemonic ‘PHATS’ stand for?

A

PRESSURE (BP > 130/85)

This indicates high blood pressure as a risk factor for metabolic syndrome.

18
Q

What does the letter H in the mnemonic ‘PHATS’ represent?

A

HDL IS LOW (<40 MEN & <50 WOMEN)

Low levels of HDL cholesterol are a risk factor for metabolic syndrome.

19
Q

What does the letter A in the mnemonic ‘PHATS’ signify?

A

ABDOMINAL GIRTH (>40IN MEN & >35IN WOMEN)

Increased abdominal girth is a critical component of metabolic syndrome.

20
Q

What does the letter T in the mnemonic ‘PHATS’ refer to?

A

TRIGLYCERIDES (>150)

Elevated triglyceride levels are associated with metabolic syndrome.

21
Q

What does the letter S in the mnemonic ‘PHATS’ indicate?

A

SUGARS (FASTING GLUCOSE >100)

High fasting glucose levels are a risk factor for metabolic syndrome.

22
Q

How many symptoms are needed for confirmatory diagnosis of metabolic syndrome?

A

3 or more

The presence of three or more risk factors is necessary for a diagnosis.

23
Q

Hormone stimulates testosterone release by the leydig cells of the testes

A

Luteinizing hormone

24
Q

What phenomenon is likely causing the patient’s increased blood glucose in the morning?

A

dawn phenomenon

This phenomenon is related to diurnal secretion patterns of hormones.

25
What is a common treatment for managing the dawn phenomenon?
* Increasing basal insulin dosing * Assessing blood glucose levels 3 to 4 hours after the last meal * Administering insulin bolus at 3 a.m. ## Footnote These steps help manage blood glucose levels effectively.
26
When should the patient check blood glucose to assess bolus dosing of insulin?
prior to dinner ## Footnote This helps in determining the appropriate bolus dosing.
27
What is the **Somogyi effect**?
A drop in glucose during the night before it rises in the morning ## Footnote This phenomenon is also known as **rebound hypoglycemia**.
28
What should a patient do to manage the **Somogyi effect**?
* Cut back PM insulin dose * Eat PM snack before bed ## Footnote These actions help prevent low blood glucose levels during the night.
29
What is the initial dosage of **Metformin** for diabetes management?
500mg daily ## Footnote This is the starting dose before considering escalation based on Hgb A1c levels.
30
If metformin was given 500 mg daily and A1c stil >7 after 3 mo thenadd metformin 500 BID and if after 3 months A1c still >7 metformin metformin 1000 BID and if A1C still high >9 gove insulin
31
What is the maximum daily dose of **Metformin**?
2500mg daily ## Footnote This is the upper limit for Metformin dosage before considering additional medications.