What is GERD?
A chronic condition where gastric contents reflux into the esophagus due to lower esophageal sphincter (LES) incompetence.
What is the pathogenesis of GERD?
LES relaxation or weakness → reflux of acid → mucosal injury → inflammation and symptoms.
What are the risk factors for GERD?
Obesity
What are the clinical features of GERD?
Heartburn
What are the complications of GERD?
Esophagitis
What are the general measures in GERD management?
Lifestyle modification: weight loss
Which drugs are used in GERD?
Proton pump inhibitors (PPIs)
What is the first-line pharmacological therapy for GERD?
Proton pump inhibitors (PPIs) are most effective for symptom relief and mucosal healing.
What is the role of H2 blockers in GERD?
Reduce nocturnal acid secretion
What is the role of prokinetic drugs in GERD?
Increase LES tone and gastric emptying
When is surgery indicated in GERD?
Severe refractory cases or complications (e.g.