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Question 1

1. Which of the following plays a role in the development of Crohn's Disease?
Select one or more:
a. gut flora (microbiota)
b. autoantibodies
c. Inflammation
d. intestinal immune system

Answer 1

a/b/c/d

Question 2

2. Which of the following plays a role in the development of Crohn's Disease?
Select one or more:
a. hereditary factors
b. gut flora (microbiota)
c. reduced gastric acidity
d. intestinal immune system

Answer 2

a/b/d

Question 3

3. What are the features of celiac disease?
   Select one or more:
   a. familial prevalence is low
   b. The most sensitive screening test is tTG IgG
   c. Megaloblastic anemia
   d. A prevalence of 10% in IgA deficiency

Answer 3

b/c/d

Question 4

4. What are the features of celiac disease?
Select one or more:
a. bloody, mucous diarrhea
b. Subfebrility/fever
c. Chronic diarrhea, abdominal pain
d. prevalence of 1%

Answer 4

b/c

Question 5

5. What are the features of celiac disease? Select one or more:
   a. dermatitis herpetiformis
   49
   Pathophysiology 1 MCQs - Team effort
   b. steatorrhea
   c. high tissue transglutanimase (tTG) IgG/IgA antibody titer

Answer 5

a/b/d

Question 6

6. What are the features of celiac disease?
Select one or more:
a. weight loss
b. type 1 hypersensitivity reaction
c. it may develop at any age
d. constipation

Answer 6

a

Question 7

7. Which ones are the potential complications of gastroesophageal reflux?
Select one or more:
a. Barrett's esophageal ulcer
b. esophageal cancer
c. achalasia
d. Barrett metaplasia

Answer 7

a/b/d

Question 8

8. Which ones are the potential complications of gastroesophageal reflux? Select one or more:
   a. Duo denal ulcer
   b. Esophageal cancer
   c. Barrett metaplasia
   d. nutcracker esophagus

Answer 8

b/c

Question 9

9. Which statements are true about ulcertive colitis (UC)?
   Select one or more:
   a. Biopsy is needed for the diagnosis
   b. The sigmoid colon and the rectum are affected in most cases
   c. An autimmune mechanism is involved in the pathogenesis of UC
   d. Colonoscopy is needed for the diagnosis

Answer 9

b/c/d

Question 10

10. Which statements are true about ulcertive colitis (UC)? Select one or more:
    a. Colonoscopy and biopsy are necessary for the diagnosis
    b. Smoking may provoke a relapse
    c. an autimmune mechanism is involved in the pathogenesis of UC
    d. It may be treated with antacids

Answer 10

a/b/c

Question 11

11. What is used in the treatment of IBD?
Select one or more:
a. antacids
b. surgical resection
c. immune suppression
d. Biological drugs (anti-TNF ab)

Answer 11

c/d

Question 12

11. What is used in the treatment of IBD?
Select one or more:
a. antacids
b. surgical resection
c. immune suppression
d. Biological drugs (anti-TNF ab)

Answer 12

a/c

Question 13

13. What features or stages may occur in Crohn's disease?
Select one or more:
a. fibrostenotic form
b. it might be asymptomatic in remission
c. fistulizing Crohn's disease
d. Reflux-type disease

Answer 13

a/b/c

Question 14

14. Which drug classes are used to block the hyperacidity?
Select one or more:
a. Proton pump inhibitors
b. Histamine H2 antagonists
c. Prostaglandin analogs
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Pathophysiology 1 MCQs - Team effort
d. Gastrin

Answer 14

a/b/c

Question 15

15. What stages may occur in Crohn’s disease?
    Select one or more:
    a. Reflux- type disease
    b. muscular hypertrophy may occur in the intestines
    c. the inflammation may penetrate deep into the tissues of the intestines
    d. dysmotility

Answer 15

b/c

Question 16

16. What can cause colorectal cancer in young adults (<40 years)? Select one or more:
    a. Lynch syndrome
    b. familial adenomatous polyposis
    c. somatic mutations of the APC gene
    d. hereditary nonpolyposis colorectal cancer (HNPCC) linked mutations

Answer 16

a/b/d

Question 17

17. Which of the following plays a role in the regulation of gastric acid production? Select one or more:
    a. gastrin
    b. histamine
    c. acetylcholine
    d. thromboxane

Answer 17

a/b/c

Question 18

18. Which ones are commonly seen in ulcerative colitis? Select one or more:
    a. anemia
    b. diarrhea, colic
    c. inflammation of the mucosa, predominantly localized to the colon
    d. superficial damage occurs to the mucosa layer

Answer 18

a/b/c/d

Question 19

19. Which one plays a role in H pylori toxin production? Select one:
    a. gastrin hypersecretion
    b. Hyperacidity
    c. Cytotoxin associated gene A (CagA)
    d. gastroesophageal reflux
    e. NOD-CARD mutation

Answer 19

c

Question 20

20. Which diseases are linked to H pylori infection? Select one or more:
    a. Gastric cancer
    b. Duodenal ulcer
    c. Mucosa associated (MALT) lymphoma
    d. Gastric ulcer

Answer 20

a/b/c/d

Question 21

22. Which are the symptoms of hyperacidity:
Select one or more:
a. Pain relief after eating
b. Nausea
c. Chest pain
d. Heartburn

Answer 21

b/c/d

Question 22

23. Which statements are true about irritable bowel syndrome?
    Select one or more:
    a. Organic diseases must be excluded before making a diagnosis
    b. It is an absorption disorder
    c. It causes a complex problem for differential diagnosis
    d. It accounts for 20% of gastrointestinal symptoms

Answer 22

a

Question 23

24. Which ones are NOT potential complications of GERD:
Select one or more:
a. Gastric ulcer
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Pathophysiology 1 MCQs - Team effort
b. Esophagus varices
c. Weight loss
d. Esophageal strictures

Answer 23

b/c

Question 24

25. Which ones are NOT potential complications of GERD:
Select one or more:
a. Esophagus varices
b. Weight loss
c. Gastric ulcer
d. Achalasia

Answer 24

a/b/d

Question 25

``` 26. Which methods can be used for colorectal cancer screening? Select one or more: a. Haemoccult test b. colonoscopy c. Tumor marker tests d. ERCP ```

Answer 25

a/b/c

Question 26

``` 27. Which method is not used in colorectal cancer screening? Select one or more: a. Hemoccult b. Tumor marker tests c. ERCP d. Colonoscop ```

Answer 26

c

Question 27

28. Which statements are false about Crohn's disease? Select one: a. It has extraintestinal manifestations b. It starts in the rectum and proceeds proximally c. it often affects the terminal ileum d. a fistula may develop e. it may cause damage to any part of the gastrointestinal tract

Answer 27

b

Question 28

``` 29. What are the potential symptoms of colon cancer? Select one or more: a. alternating diarrhea and constipation b. jaundice c. bloody stools d. anemia ```

Answer 28

a/c/d

Question 29

``` 30. Which drug classes can reduce the hyperacidity? Select one or more: a. Histamine H2 receptor antagonists b. NSAIDs c. Antacids d. Gastrin ```

Answer 29

a/c

Question 30

``` 31. Pathogenic factors of H pylori: Select one or more: a. Hyperacidity b. Cytotoxin associated gene a (Caga) c. Inflammation d. Endotoxin (LPS) ```

Answer 30

b/d

Question 31

``` 2. What are the potential complications of reflux disease? Select one or more: a. peptic ulcer b. weight loss c. achalasia d. esophageal strictures ```

Answer 31

d

Question 32

33. Which drug is not used in H pylori eradication protocols? Select one: a. clarithromycin+amoxicillin (combined antibiotics treatment) 55 Pathophysiology 1 MCQs - Team effort b. Proton pump inhibitor c. Bismuth d. metronidazole (antibiotic covering the anaerobic bacteria) e. NSAIDs

Answer 32

e

Question 33

33. Which drug is not used in H pylori eradication protocols? Select one: a. clarithromycin+amoxicillin (combined antibiotics treatment) 55 b. Proton pump inhibitor c. Bismuth d. metronidazole (antibiotic covering the anaerobic bacteria) e. NSAIDs

Answer 33

e

Question 34

34. Which methods are not used in colorectal cancer screening?a. ERCP b. Hemoccult test c. esophagogastroduodenoscopy (EGD) d. Colonoscopy

Answer 34

a/b