liver

Question 1

1. Which materials are primarily excreted in the liver?
Select one or more:
a. bilirubin
b. cholesterol
c. copper
d. iron

Answer 1

a/b/c

Question 2

2. The most common cause of severe acute parenchymal liver lesion in the US:
Select one:
a. acute alcohol intoxication
b. mushroom poisoning
c. paracetamol overdose
d. viral hepatitis
e. cocaine overdose

Answer 2

c

Question 3

3. Chronic hepatitis is never caused by:
Select one of more:
a. HDV
b. HBV
c. HAV
D. HCV
4.

Answer 3

c

Question 4

4. What percentage of deaths occurring under 70 years of aging Hungary are related to alcohol consumption:
Select one:
a. 5%
b. 10%
c. 15%
d. 20%
E. 25%

Answer 4

d

Question 5

5. Clinical signs of liver disease include:
Select one or more:
a. palmar erythema
b. koilonychia
c. hypertrichosis
d. spider nevi

Answer 5

a/d

Question 6

6. Consequences of cirrhosis in the liver:
Select one or more:
115
Pathophysiology 1 MCQs - Team effort
a. fewer microvilli on the liver cells
b. capillarization of sinusoids
c. loss of parenchyma
d. more collagen production

Answer 6

a/b/c/d

Question 7

7. Which infection cannot be prevented by vaccination?
Select one:
a. HDV
b. HAV
c. HCV
d. HEV
e. HBV

Answer 7

c

Question 8

8. Laennec cirrhosis is caused by:
Select one:
a. alcohol
b.drug effect
c. biliary obstruction
d. Wilson's disease
e. congestive heart failure.

Answer 8

a

Question 9

9. Cirrhosis may cause the following except:
Select one:
a. bleeding tendency
b. spontaneous bacterial peritonitis
c. hepatocellular carcinoma
d. hepatorenal syndrome
e. iron deficiency

Answer 9

e

Question 10

10. It is true about HCV infection:
    Select one or more:
    a. there is no effective vaccine against it
    b. there is not effective antiviral drug against it
    c. it is most likely to turn into chronic hepatitis
    d. fulminant course is common

Answer 10

a/c

Question 11

11. Both portal hypertension and decreased parenchyma contribute in cirrhotic patients to the development of:
Select one or more:
a. prolonged protrombin time
b. ascites
c. hepatic encephalopathy
d. splenomegaly

Answer 11

b/c

Question 12

12. The consequence of an increased NADH/NAD ratio in the liver of alcoholic patients:
    Select one or more:
    a. MEOS is induced
    b. beta-oxidation of fatty acids is inhibited
    c. citrate cycle is inhibited
    d. gluconeogenesis is inhibited

Answer 12

b/c/d

Question 13

13. Which nutrients coming through the portal vein are filtered and stored in the liver?
Select one or more:
a. fatty acids and monoglycerides
b. ketone bodies
c. amino acids
d. glucose

Answer 13

c/d

Question 14

14. What is the idiosyncratic reaction?
    Select one:
    a. severe adverse effect resulting from the interaction of more than two drugs
    b. severe adverse effect resulting from the interaction of two drugs
    c. when two different drugs have the same adverse effect
    d. drug poisoning of mentally retarded people
    e. severe adverse effect of a drug administered at the usual dose

Answer 14

e

Question 15

15. Asterixis is a symptom occurring in hepatic encephalopathy. What is it?
    Select one:
    a. visual disturbance: seeing star-like lights
    b. the name of convulsions seen in this state
    c. momentarily losing the ability to hyperextend the wrist joint
    d. reading cartoons obsessively
    e. reversal of the sleep/wake pattern

Answer 15

b

Question 16

16. Alcohol consumption is toxic to the:
Select one or more:
a. gastrointestinal tract
b. nervous system
c. liver
d. muscle

Answer 16

a/b/c/d

Question 17

17. In patients with liver failure who have high levels of ammonia in the plasma
    select one or more:
    a.The activity of glutamine synthetase is increased in the muscle
    b.The activity of glutamine synthetase is increased in the liver
    c.The amount of glutamate is increased in the synapses of the brain
    d.The amount of glutamate is increased in the astrocytes

Answer 17

a

Question 18

18. Liver disease may cause
select one or more:
a.Fatty liver
b.Hyperglycemia
c.Hypoglycemia
d.Bleeding tendency

Answer 18

a/b/c/d

Question 19

19. Laënnec cirrhosis is caused by
select one:
a.Biliary obstruction
b.Congestive heart failure
c.Alcohol
d.Wilson´s disease
e.Drug effect

Answer 19

c

Question 20

20. Consequence of cirrhosis in the liver
select one or more:
a.More collagen production
b.Fewer microvilli on the liver cells
c.Capillarization of sinusoids
d.Loss of parenchyma

Answer 20

a/b/c/d

Question 21

21. What is the likelihood that an HBV infection become chronic in a newborn?
select one:
a.0%
b.1-10%
c.10-20%
d.40-50%
e.90%

Answer 21

e

Question 22

22. What is hepatorenal syndrome?
    select one:
    a.Severe impairment of liver function seen in kidney disease
    b.Severe impairment of renal function seen in liver disease
    c.Severe lesion of the liver parenchyma seen in kidney disease
    d.Any condition in which there is a simultaneous liver and kidney dysfunction
    e.Severe lesion of the kidney parenchyma seen in liver disease

Answer 22

b

Question 23

23. Symptoms of hepatic encephalopathy, except:
    Select one:
    118

a. foetor hepatis
b. vomiting
c. paralysis
d. asterixis
e. reversal of sleep/wake cycle

Answer 23

c

Question 24

24. Foetor hepatis is the name of:
Select one:
a. alcoholic cirrhosis
b. the characteristic smell of the breath of cirrhotic patients
c. alcoholic steatohepatitis
d. alcoholic steatosis
e. the fetal liver

Answer 24

b

Question 25

``` 25. Which clinical states are associated with a higher risk for hepatocellular carcinoma? Select one or more: a. NAFLD b. cirrhosis c. NASH d. chronic HBV infection ```

Answer 25

b/d

Question 26

``` 26. Which hereditary condition may cause progressive parenchymal lesion in the liver? Select one or more: a. Gilbert’s syndrome b. hemochromatosis c. Wilson’s disease d. hemophilia ```

Answer 26

b/c

Question 27

``` 27. The increase of which enzyme activity indicates the lesion of liver parenchyma? Select one: a. ALAT b. GGT C. ALP d. LDH e. CPK ```

Answer 27

a

Question 28

``` 28. Which materials are stored in the liver? Select one or more: a. nutrients b. ketone bodies c. iron d. vitamines ```

Answer 28

a/c/d

Question 29

``` 29. In which Viral hepatitis is pregnancy a risk factor for a fulminant course? Select one: a. HEV b. HCV c. HDV d. HAV e. HBV ```

Answer 29

a

Question 30

30. The ammonia level of plasma is decreased by the: Select one or more: a. decreased activity of glutamine synthetase in the muscle b. increased activity of glutamine synthetase in the liver c. increased activity of urea cycle d. increased intake of proteins

Answer 30

b/c

Question 31

``` 31. The tolerance for barbiturates in alcoholics is: Select one or more: a. decreased in the drunken state b. decreased in the sober state c. increased in the drunken state d. increased in the sober state ```

Answer 31

a/d

Question 32

``` 32. Caput medusae” is the name: Select one: a. for dilated capillaries b. for spider nevi c. of the dying jellyfish d. when someone dies from the sting of a jellyfish e. for dilated periumbilical veins ```

Answer 32

e