Hematologic Disorders 3

Question 1

Special considerations for hematologic disorders: should make sure to look at changes with this

Answer 1

coagulation

Question 2

consider these with respect to changes in coagulation in pts with hematologic disorders:

Answer 2

• increased risk of thrombus
• increased work for heart
• breathing
• tissue perfusion

Question 3

Platelet disorders are very important to consider with respect to this! (PT)

Answer 3

exercise prescription

Question 4

normal platelet range

Answer 4

150,000-400,000 per microliter of blood

Question 5

PT prescription: platelet range = 40-60,000

Answer 5

• keep exercise in low-load (1-2#) resistance

- OK for walk, bike, ADLs

Question 6

PT prescription: platelet range = 20-40,000 per microliter of blood

Answer 6

• low intensity

- no resistance

Question 7

PT prescription: platelet range = below 10,000 per microliter of blood means the pt is at risk for

Answer 7

spontaneous bleed

Question 8

Why must clotting precautions be taken with a pt who has splenomegaly?

Answer 8

Splenomegaly is usually associated with rapid destruction of blood cells

Question 9

PT implications with splenomegaly

Answer 9

Avoid activities or positions that could traumatize abdomen or increase pressure

Question 10

What can exercise and sports do with respect to blood volume and erythrocytes for pts with hematologic disorders?

Answer 10

• can increase blood volume (plasma) immediately

- increase erythrocytes over time

Question 11

Blood doping through:

Answer 11

exogenous EPO

Question 12

Blood doping through exogenous EPO can increase these in pts with hematologic disorders:

Answer 12

• blood viscosity
• thrombus formation

risky process

Question 13

In general, there is a possible indication of hypovolemia any time there’s a combination of:

Answer 13

• systolic BP drop of 20 points or more

- Increased HR of 15 BPM or more

Question 14

What is the most likely cause of hypovolemia in pts with hematologic disorders?

Answer 14

dehydration

Question 15

What are possible causes of hypovolemia in pts with hematologic disorders?

Answer 15

• dehydration (most likely)
• diarrhea
• slow GI bleed
• May be normovolemic but on antihypertensives

Question 16

Blood transfusions: Modern techniques available to only administer the necessary component (what are they)

Answer 16

• Packed RBCs

- Plasma

Question 17

Packed RBCs needed for

Answer 17

anemia

Question 18

Plasma needed for

Answer 18

coagulation deficiencies

Question 19

Recombinant human erythropoietin products:

Answer 19

• rHuEpo
• EPO
• Epogen

Question 20

Function of recombinant human erythropoietin products

Answer 20

• stimulate erythropoietin

- elevate RBCs