1
Q
Brand Name
A
Cyanokit
2
Q
Drug Class
A
Antidote
3
Q
Mechanism of Action
A
Binds directly to cyanide forming cyanocobalamin (Vitamin B12) which is readily excreted
4
Q
Indications
A
Known or suspected cyanide poisoning
5
Q
Contraindications
A
None
6
Q
Adverse Effects
A
HTN, allergic rxn have been reported, N/V, dyspnea, indigestion, dizziness, bright red skin pigmentation that can last several days
7
Q
Precautions
A
Not compatible in same IV line w/ many other medications
8
Q
Dose and Administration
A
5g IV infusion @ 15mL/minute over 15 mins
May repeat one time
Pedi: 70mg/kg, same infusion rate
Pharmacology
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