1
Q
Brand Name
A
Osmitrol
2
Q
Drug Class
A
Osmotic Diuretic
3
Q
Mechanism of Action
A
Decrease cerebral edema and intracranial pressure
Promotes urinary excretion of toxins
4
Q
Indications
A
Cerebral edema, increased ICP, rhabdomyolysis, blood transfusion reactions
5
Q
Contraindications
A
Hypotension, pulmonary edema, severe dehydration, CHF, active intracranial bleed
6
Q
Precautions
A
May precipitate digitalis toxicity
7
Q
Adverse Effects
A
H/A, confusion, seizures, pulmonary edema, tachycardia, CP, CHF, hypotension, N/V, dehydration
8
Q
Dose and Administration
A
0.5-1.0g/kg IVP over 5-10 minutes
Infusion of 0.25-2g/kg over 4-6 hours prn
Pharmacology
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