hypertension

Question 1

• PO before meals to increase absorption
• AE: persistent dry cough, angioedema, compromised airway, orthostatic hypotension
• CI pregnancy, foods high in salt/potassium
• drug/drug: NSAIDs, potassium sparing diuretics
• ACE inhibitor

Answer 1

captopril

Question 2

• blocks effect angiotensin II by blocking receptor sites –> decreases SVR
• PO
• AE: orthostatic hypotension
• CI pregnancy
• low sodium & fat diet
• don’t crush

Answer 2

losartan

Question 3

• dilate peripheral arteries & decrease PVR
• PO, same time daily
• AE: peripheral edema, orthostatic hypotension, constipation
• food/drug: grapefruit

Answer 3

diltiazem

Question 4

• dilates blood vessels & decreases PVR
• PO, generally at bedtime
• AE: first dose phenomenon, sodium & fluid retention

Answer 4

doxazosin

Question 5

doxazosin is a(n)

Answer 5

alpha1 blocker

Question 6

• stimulates alpha2 receptors which leads to decreased sympathetic outflow from CNS & lower BP
• Po or transdermal (2-3 days effect)
• AE: CNS effects, nightmares

Answer 6

clonidine

Question 7

clonidine is a(n)

Answer 7

alpha2 agonist

Question 8

• decreases HR, contractility, renin release
• PO, IV
• CI bradycardia, hypotension
• AE: GI upset. HF, pulmonary edema, hypotension

Answer 8

propanolol

Question 9

propanolol is a

Answer 9

beta blocker