nausea/vomiting

Question 1

• prevention/treatment nausea, vomiting for surgery, anesthesia, migraines, chemo, & motion sickness
• BBW <2yrs (resp depression)
• CI parkinson’s, SQ admin
• AE: blurred vision, urinary retention, dry mouth, photosensitivity, drowsiness, confusion, tissue injury IV
• preferred route IM

Answer 1

promethazine (phenergan)

Question 2

promethazine is a

Answer 2

phenothiazine

Question 3

T/F: take promethazine before causative event

Answer 3

T

Question 4

• prevents histamine effects on body
• used as antiemetic, prevention motion sickness, sedative for anxiety treatment
• AE: drowsiness, confusion, dry mouth, thickened resp secretions, blurred vision, urinary retention, tachycardia
• SQ/IV admin can result in tissue injury
• CI renal/liver impairment

Answer 4

hydroxyzine (Vistaril)

Question 5

hydroxyzine is a(n)

Answer 5

antihistamine

Question 6

• prevent/treat moderate to severe nausea/vomiting for cancer chemo, radiation, postop status
• AE: diarrhea, headache, dizziness, pain at injection site, fatigue, constipation
• CI: antidysrhythmic drugs (Qt interval prolongation)
• oral disintegrating, IM, IV

Answer 6

ondansetron (Zofran)

Question 7

ondansetron is a

Answer 7

serotonin receptor antagonist

Question 8

• stimulates motility upper GI tract, increases lower esophageal sphincter, block dopamine receptors at chemoreceptor trigger zone
• AE: TD, CNS effects, life-threatening bradycardia, SVT, tachycardia, agranulocytosis, neutropenia, seizures, SI, NMS
• BBW: irreversible TD
• monitor bowel sounds

Answer 8

metoclopramide hydrochloride

Question 9

metoclopramide hydrochloride is a

Answer 9

dopamine antagonist