Anterior hypothalamus
above the optic chiasm
supraoptic
medial hypothalamus
above the pituitary
tuberal
posterior hypothalamus
above and including the mammillary bodies
Anterior HT region nuclei
Tuberal Hypothalamic Nuclei (posterior)
Tuberal HT nuclei (ant)
Posterior Hypothalamic Nuclei
Autonomic System:
ability of HT to regulate ANS is critical for its role in maintaining homeostasis and inducing emotional expression.
Efferent/afferent pathways from the hypothalamus to the ANS travel in the following tracts:
Dorsal longitudinal fasiculus:
to ANS nuclei in the brainstem reticular system
Medial forebrain bundle:
to brainstem reticular formation
Mammillotegmental tract:
from mammillary bodies to midbrain reticular formation (tegmentum)
In general, stimulation of the anterior hypothalamus results in:
increases PNS activity (or SNS actions) stimulation of the posterior hypothalamus increases SNS activity.
Somatic Motor System:
HT neurons innervate neurons in:
the reticular formation of the brainstem near the motor nuclei of the cranial nerves. These somatic neurons in turn innervate skeletal muscle.
Use same pathways as those used for the ANS
Endocrine system:
HT regulates hormone release from both anterior & posterior lobes of the pituitary.
Posterior pituitary:
Anterior pituitary:
HT synthesizes and releases hormones into hypothalamo-pituitary portal circulation that regulate release of hormones from the anterior pituitary.
Ant pituitary portal system
carries these hormones directly to the endocrine cells of the anterior pituitary w/o being diluted by general circulation
HT hormones
regulate the release of anterior pituitary hormones
Anterior pituitary hormones
regulate the release of hormones from most peripheral endocrine organs
HT ____ most of endocrine system
indirectly regulates
Limbic system:
Appropriate initiation of motivated behaviors and integration of emotional expression with sensory and environmental cues requires connections between the hypothalamus and the limbic system.
structures of limbic system