Ipratropium Bromide

Question 1

Drug class

Answer 1

Anticholinergic agent

Question 2

Pharmacology

Answer 2

An antimuscarinic agent which promotes bronchodilation by inhibiting cholinergic bronchomotor tone

Question 3

Metabolism

Answer 3

Hepatic with excretion by the kidneys

Question 4

Indications

Answer 4

Moderate to severe bronchospasm

*in moderate cases pt must be unresponsive to initial salbut NEB

Question 5

Contraindications

Answer 5

• Allergy and/or adverse drug reaction

* Pts <1yr

Question 6

Precautions

Answer 6

Glaucoma

Question 7

Side effects

Answer 7

• Dilated pupils
• Dry mouth
• Palpitations

Question 8

Presentation

Answer 8

250mcg/1ml

Question 9

Onset

Duration

Answer 9

O: 1.5-3min

D: 4-6hrs

Question 10

Routes of administration

Answer 10

Nebuliser (NEB)

*MUST be admin in conjunction with NEB salbutamol

Question 11

Adult dosages

Answer 11

NEB 500mcg, repeated @ 20mins, total max dose 1.5mg

Question 12

Paediatric dosages

Answer 12

≥6yrs
• 500mcg, repeated @ 20mins, total max dose 1.5mg

1-5yrs
• 250mcg, repeated @ 20mins, total max dose 750mcg