Methoxyflurane

Question 1

Drug class

Answer 1

Analgesic at low doses

Question 2

Pharmacology

Answer 2

Volatile self-administered inhalation analgesic indicated for short term-pain relief that has a great propensity to diffuse into fatty tissue

Question 3

Metabolism

Answer 3

By the liver & excreted mainly by the lungs

Question 4

Indications

Answer 4

Pain

Question 5

Contraindications

Answer 5

• Allergy and/or adverse drug reaction
• < 1yr
• Hx significant liver or renal disease
• Hx malignant hyperthermia

Question 6

Precautions

Answer 6

• ALOC

* Intoxicated or drug affected pts

Question 7

Side effects

Answer 7

• ALOC
• Cough
• Renal / hepatic failure (following repeated High dose expose)

Question 8

Presentation

Answer 8

3ml bottle

Question 9

Routes

Onset

Duration

Answer 9

INH

1-3mins

5-10mins

Question 10

Dosages

Answer 10

Adult
INH 3ml, repeated after 20mins, total max dose 6ml

Paediatric ≥ 1yr
INH 3ml, single dose only