Metabolism

Question 1

Metabolism

Answer 1

a chemical alteration of a drug by the living system to enhance water solubility and excretion

Question 2

Factors affecting metabolism

Answer 2

Structure of drug
structure complexity (sites for metabolism)
blocked altered site for metabolism

Question 3

Phase 1

Answer 3

Functional group changes, make sites for conjugation

Question 4

Phase 2

Answer 4

Conjugation to hydrophilic units