Methadone

Question 1

Introduction of the drug

Answer 1

• Used as a substitute to heroin
• Class A/Schedule 2
• POM

Question 2

Pharmacodynamics

Answer 2

• Acts on opioid receptors

- Potassium ions increases making the cell hyper polarised

Question 3

Pharmacokinetics

Answer 3

• Absorption in GI tract
• Wide spread distribution
• Metabolised in the liver
• Excreted in the kidneys

Question 4

Side Effects

Answer 4

• Cns effects, analgesia, euphoria, sedation, rest depression