Module 3 Flashcards

Mood Disorders and Suicide (52 cards)

1
Q

Mood Disorders

A

Classified in two broad categories unipolar and bipolar

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2
Q

Depressive Disorders

A

Involve change in mood in direction of depression. Major Depressive Disorder; Persistent Depressive Disorder

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3
Q

Bipolar and Related Disorders

A

Involve periods of depression cycling with periods of mania. Bipolar I; Bipolar II; Cyclothymia; Rapid Cycling Specifier

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4
Q

Major Depressive Disorder

A

“Common cold” of mental disorders. Exists on a continuum (mild feelings of sadness to the severe, persistent, debilitating feelings)

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5
Q

Diagnostic Criteria (MDD)

A

Five or more of the following symptoms have been present during the same 2 week period and represent a change from previous functioning. At least 1 symptom is either (1) depressed mood or (2) loss of interest.

1) Depressed mood most of the day, nearly everyday or observation by others
2) Diminished interest or pleasure in all, or almost all activities of the day, nearly every day
3) Significant weight loss when not dieting or weight fain or decrease or increase in appetite nearly everyday
4) Insomnia or hypersomnia nearly every day
5) Psychomotor agitation or retardation nearly every day
6) Fatigue or loss of energy nearly every day
7) Feelings of worhtlessness or excessive or inappropiate guilt (which may be delusional) nearly every day
8) Diminished ability to think or concentrate, or indecisiveness, nearly every day
9) Recurent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for commiting suicide

Symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning

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6
Q

Persistent Depressive Disorder

A

A chronic low mood lasting for at least two years, along with at least three associated symptoms (may also experience recurrent episodes of MDD)

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7
Q

PDD Criteria

A

Depressed mood for most of the day, for more days than not, indicated by either subjective account or observation by others for at least 2 years (in children and adolescents, mood can be irritable and duration must be at least 1 year)

Presence while depressed for two (or more) of the following:

1) Poor appetite or overeating
2) Insomnia or hypersomnia
3) Low energy or fatigue
4) Low self esteem
5) Poor concentration or difficulty making decisions
6) Feelings of hopelessness

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8
Q

Mania

A

Distinct period of elevated, expansive or irritable mood that lasts at least one week and is accompanied by at least three associated symptoms

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9
Q

Hypomania

A

Less severe form of mania that involves a similar number of symptoms, but those symptoms need to be present for only four days

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10
Q

Bipolar I

A

Individual has a history of one or more manic episodes with or without one or more major depressive episodes

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11
Q

Bipolar II

A

Defined as a history of one or more hypomanic episodes with one or more major depressive episodes

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12
Q

Diagnostic Criteria for Manic Episode

A

Distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally and persistently increased goal directed activity or energy, lasting at least one week and present most of the day nearly everyday.

During the period of mood disturbance and increased energy or activity, three (or more) of the following symptoms (four if mood is only irritable) are present to a significant degree and represent a noticeable change from usual behaviour

1) Inflated self esteem or grandiosity
2) Decreased need or sleep (eg. feels rested after only 3 hours for sleep)
3) More talkative than usual or pressure to keep talking
4) Flight of ideas or subjective experience that thoughts are racing
5) Distractability (eg attention too easily drawn to unimportant or irrelevant external stimuli), as reported or observed
5) Increase in goal directed activity (either socially, at work or school or sexually) or psychomotor agitation (eg. purposeless non goal directed activity)
7) Excessive involvement in activities that have a high potential for painful consequences (eg. engaging in unrestrained buying sprees, sexual indiscretions, or foolish business investments)

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13
Q

Cyclothymia

A

Chronic less severe form of bipolar disorders. Involves a history of at least two years of alternative hypomanic episodes and episodes of depression that do not meet the full criteria for major depression. Mood swings are mild and hypomania may be enjoyable –> often do not seek treatment

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14
Q

Rapid Cycling Specifier

A

Presence of four or more manic and/or major depressive episodes in a 12 - month period. Episodes are separated by at least two months or by a switch to the opposite mood state

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15
Q

Seasonal Affective Disorder (SAD)

A

Recurrent depressive episodes tied to the changing seasons. Focused on melatonin - as the sun provides increased light in the morning, melatonin release is normally lowered causing body temps to rise, triggering the body process to move to their awake state. May need more light to trigger decreased melatonin secretion

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16
Q

Mood Disorders with Peri or Postpartum Onset

A

Women can experience mood swings and feelings of depression up to two weeks after childbirth. Most of the time theses symptoms resolve themselves but sometimes it’s chronic. Mood disorders can occur in the peripartum period, which refers to the last month of gestation or the first few months after delivery

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17
Q

Premenstrual Dysphoric Disorder (PMDD)

A

Characterized by marked affective lability, irritability/anger, depressed mood, and/or anxiety, plus the presence of additional symptoms of loss of interest in activities, concentration difficulties, low energy, changes in appetit and/or sleep, feelings of loos of control, and/or physical symptoms. 5 symptoms must be present to meet DSM - 5 criteria and they must interfere with the woman’s functioning. Symptoms must be present fo rmost menstrual cycles in the year.

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18
Q

Psychodynamic Personality Theories (Etiology)

A

Blatt theories that these personality styles, which develop as a function of maladaptive parenting styles and/or traumas early in development, render people vulnerable to depression when they face a stressful life event that triggers the personality theme

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19
Q

Cognitive Theories

A

All or nothing thinking; Overgeneralization; Magnification (catastrophizing); Jumping to conclusions; Diathesis Stress Model

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20
Q

Cognitive Distortions

A

Aaron T. Beck proposed that a person’s emotional response to a situation is determined by how they evaluate it. People with depression/prone to depression are more likely to appraise situations negatively –> more likely to experience negative mood in response to such situations

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21
Q

All or Nothing Thinking

A

Se things in black or white categories (ex. getting a C on a math exam and thinking “total failure”)

22
Q

Overgeneralization

A

See a single negative event as a never ending pattern of defeat by using words such as “always” or “never” when thinking about it (ex. late for a dr appt “I am always screwing up”)

23
Q

Magnification (Catastrophizing)

A

Exaggerate the importance of your errors or problems (ex. forget someone’s name when introducing him/her and you tell yourself “this is terrible”)

24
Q

Jumping to Conclusion

A

Interpret things negatively when there are no definite facts to support your conclusion (ex. Your partner doesn’t return your call and you think they don’t care about you buy they are busy visiting a grandparent)

25
Diathesis Stress Model
Created by Beck and states that psychological disorders result from an interaction between inherent vulnerability and environmental stress
26
Interpersonal Models
Key feature of depression is interpersonal relationships. Negative feedback seeking; Excessive reassurance seeking; Stress generation hypothesis
27
Negative Feedack Seeking
Tendency to actively seek out criticism and other negative interpersonal feedback
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Excessive Reassurance Seeking
Tendency to seek assurance about one's worth and lovability
29
Stress Generation Hypothesis
Depressed individuals have been found to generate stressful life events int he interpersonal domain, including fights, arguments and interpersonal rejection
30
Life Stress Perspective
Stressful life events tax on our psychological and physical resources and can cause significant increases in sadness, anxiety, and irritability. Stressful life events can trigger a downward spiral into major depression
31
Childhood Stressful Life Events
Early maltreatment is internalized by the child in the form of negative cognitive schemas such as "I'm unlovable", "People are out to hurt me", "The world is a dangerous place". Childhood trauma is related to development of negative cognitive schemas about the self that are then related to the development of depression. Child abuse is associated with teh death of cells in the hippocampus and amygdala, two areas of the brain are critically involved in the regulation of mood and emotional memory.
32
Biological Causal Factors
Genetics, Neurotransmitters, Stress and the Hypothalamic Pituitary Adrenal Axis, Sleep Neurophysiology
33
Genetics (MDD)
First degree relatives are 2 -5 times more likely to develop depression
34
Genetics (Bipolar Disorder)
First degree relatives of people with bipolar disorders are at a 7 -15 times greater risk of developing any mood disorder
35
Adoption Study
Method that has been used to tease family environment from genetic contribution to mood disorders. Found that genetics impact disorders
36
Twin Studies
Used to support a genetic cause for the mood disorder. Monozygotic twins are more genetically similar
37
Genetic Contributions
There is no single "mood disorder gene" but a number of candidate genes have been examine. HTT (serotonin transporter gene) can either be a short "s" or a long "l"
38
"l" Allelle
Greater activity of the gene and higher function of serotonin in the brain
39
"S" Alelle
Associated with negative cognitive style that is vulnerable to depression
40
Nuerotransmitters
Can have excitatory effects if postsynaptic neurons, increasing their chances of firing new action potentials, or can have inhibitory effects reducing the chances of their firing
41
Neurotransmitter Systems in Depression
Catecholamine norepinephrine (NE) and Indoleamine serotonin (5-hydroxytryptamime, or 5-HT) were both found to be responsible for functions disturbed in depression (sleep, appetite, energy and activity level). Depression was caused by deficit of 5-HT, NE or DA activity, mania was caused by too much NE or DA activity in the context of too little 5-HT activity. NE, DA, 5-HT are also theorized to play a role in manic episodes of bipolar disorder
42
Stress and The Hypothalamic Pituitary Adrenal Axis
Stress is modulated through the hypothalamic pituitary adrenal (HPA) axis. More chronic stress result in sustained release of cortisol and a breakdown of the negative feedback inhibition of the HPA axis - prolonged periods of cortisol hypersecretion have been fount to kill brain cells and cause permanent damage to the hippocampus. Depressed individuals show elevated levels of cortisol and have smaller hippocampal volume
43
Sleep Neurophyisiology
When suffering from depression, people experience a loss of slow wave sleep and an early onset of first REM stage, as well as higher frequency and amplitude of eye movements during REM sleep - too much REM sleep
44
Neuroimaging (Depression & Bipolar)
Research using positron emission tomography (PET) has demonstrated that both bipolar and unipolar depression are associated with decreased blood glow and reduced glucose metabolism in the frontal regions of the cerebral cortex
45
Suicide
The intentional taking of one's own life
46
Suicide Risk Factors
Being male, cultural ethnic and regional variation (low in Canada and US, high in Germany Scandinavia, Eastern Europe, and Japan). Poverty, school failure, family violence, and high rates of substance abuse are also strong contributing factors in these communities
47
What Causes Suicide?
Mental Disorder, Social Contextual Factors, Biological Factors, Psychological Factors
48
Mental Disorder (Suicide)
Number one cause of suicide is untreated mental disorder
49
Social Contextual Factors
The less people feel integrated in their society, the greater the sense of anomie among society numbers, hence, the higher rates of suicide
50
Biological Factors (Suicide)
Family/genetics - if they have mood disorders or not
51
Psychological Factors (Suicide)
Interpersonal Model: High levels of perceived burdensomeness and thwarted belongingness along with feelings of hopelessness about the future lead to suicidal ideation Motivational Volitional Model of Suicide: Cognitions of defeat, humiliation and entrapment in response to stressful life events will result in a motivation for suicidal ideation
52
Prevention (Suicide)
Canadian federal government has passed legislation supporting a national suicide prevention strategy. Prevention include board public education programs, suicide prevention centres and telephone hotlines