Morphine

Question 1

Morphine MOA

Answer 1

Mu opioid receptor agonist

-can cause histamine release and hypotension

Question 2

Morphine BBW

Answer 2

Hypotension

***respiratory depression leading to sedating effects ; ER DO NOT CRUSH

Question 3

Morphine dosing

Answer 3

Post-op pain: 1-4 mg q1-4 hrs PRN; up to 10 mg q2-4 hrs PRN for severe pain
Noncancer pain: 2-5 mg q2-4 hrs PRN
Palliative care: 2-5 mg q3-4 hrs PRN