Rate Limiting Steps

Question 1

Glycolysis

Answer 1

PFK-1

activated when insulin dec cAMP so protein kinase A inactive - favors PFK2

Question 2

Gluconeogenesis

Answer 2

Fructose - 1,6 bisphosphate

When fasting glucagon inc cAMP to inc protein kinase A - favors fructose bisphosphatase 2

Question 3

TCA Cycle

Answer 3

Isocitrate DH

Question 4

Glycogenesis

Answer 4

Glycogen synthase

Question 5

Glycogenolysis

Answer 5

Glycogen phosphorylase

Question 6

HMP Shunt

Answer 6

Gluc- 6- phos DH (G6PD)

Question 7

De Novo Pyrimidine Synthesis

Answer 7

Carbomyl Phos Synthetase II

Question 8

De Novo Purine Synthesis

Answer 8

Glutamine - PRPP - amidotransferase

Question 9

Urea Cycle

Answer 9

Carbomyl Phos Synthetase I

Question 10

FA Synthesis

Answer 10

Acetyl CoA Carboxylase

Question 11

Ketogenesis

Answer 11

HMG CoA Synthase

Question 12

Cholesterol Synthesis

Answer 12

HMG CoA Reductase