Where does it occur?
In the proximal convoluted tubule
What is selective reabsorption?
The process of reabsorbing substances like glucose amino acids from the PCT into the blood
Ensures useful molecules are retained and waste products e.g. urea are excreted
1st step?
Sodium ions are actively transported out of the PCT epithelial cells into surrounding capillaries, using ATP and sodium-potassium pumps
Creates a low Na+ concentration inside the epithelial cells
2nd step?
Sodium ions move into the PCT cells from the lumen down the conc gradient via co-transport proteins
As sodium diffuses, it brings glucose/amino acids with it
3rd step?
Glucose/amino acid is now in the PCT cell so can leave by facilitated diffusion into the blood capillaries
(High concentration in the PCT cell and a low concentration in the blood)
4th step?
As solutes are reabsorbed, water follow by osmosis, down the water potential gradient
85% of water is reabsorbed at this stage
Microvili?
Increases surface area for reabsorption
Many mitochondria?
Provides ATP for active transport of Na+
Basal infoldings?
They are folds in the membrane at the base of the PCT cells containing Na/K+ pumps
Increases surface area for Na+/K+ pumps
Many carrier proteins?
For co-transport of glucose and amino acids
Channel proteins?
Facilitated diffusion of glucose and amino acids