STAPHYLOCOCCUS

Question 1

OVERVIEW OF THE GENUS STAPHYLOCCOCUS

coagulase positive- ________
coagulase negative ________ & ______ & __________

Answer 1

s. aureus

s. epidermidis; s. saprophyticus; and s. lugdunensis

Question 2

ANTIGENIC STRUCTURES
____________ among the microbial surface components recognizing adhesive matrix molecules

binds to _____ portion of IgG molecules except IgG3

Answer 2

protein A
binds to Fc portion of IgG molecules except IgG3

Question 3

ENZYMES:
1. ______ - breaks down hydrogen peroxide into water and O2
2.______ - clots plasma forms protective fibrin coats –> facilitates evasion
3.______ - another MSCRAMM forms clumps when mixed with plasma
4. _________ - spreading factor and causes fibrinolysis

Answer 3

catalase
coagulase
clumping factor
hyaluronidase

Question 4

TOXINS
_________: lyse red blood cells and other cells types contributing to tissue damage
_________: kills white blood cells an important virulence factor in community acquired MRSA
_________: acts as a superantigen leading to the symptoms of toxic shock syndrome (TSS)

Answer 4

1. Hemolysins
2. Panton-Valentine Leukocidin
3. Toxic shock syndrome Toxin-1