TOGAVIRIDAE

Question 1

RUBELLA REPLICATION
A. Rubella virus uses the _______ as its primary factory for maturation and assembly

Answer 1

Golgi Apparatus

Question 2

RUBELLA CLINICAL
-> _______ rash + post auricular and suboccipital lymphadenopathies
-> in women they have transient _______ due to immune complexes
-> complications include TP and E

Answer 2

1. morbilliform rash
2. transient polyarthritis
3. thrombocytopenic purpura and encephalitis

Question 3

CONGENITAL RUBELLA
3 POSSIBLE EFFECTS
1. ______transient effects in infants: growth retardation, rash and hepatosplenomegaly
2. ________ manifestations such as the classic triad
-> cataracts, cardinal abnormalities, deafness
3. _________ abnormalities that appear and progress during childhood and adolescence

COMPLICATION RARE:
_______ happens in the 2nd decade of life which progress to death

Answer 3

1. transient effects
2. permanent effects
3. developmental abnormalities
4. Progressive Rubella encephalitis

Question 4

CHIKUNGUNYA
VECTOR: AA or AAlb
Joint Pain: ________
Hemorrhage and Shock/Organ failure is ___

Answer 4

Join pain is SEVERE
Hemorrhage and shock/organ failure is very rare

Question 5

EASTERN EQUINE ENCEPHALITIS VIRUS
1. Vector: _________ mosquito (Cullesta) or Aedes
2. Reservoir: wild birds

WESTERN EQUINE ENCEPHALITIS VIRUS
1. More common and less severe
2. Vector: _______
3. Reservoir: _________

Answer 5

EASTERN EQUINE ENCEPHALITIS VIRUS
1. Vector: swamp mosquito (Cullesta) or Aedes
2. Reservoir: wild birds

WESTERN EQUINE ENCEPHALITIS VIRUS
1. More common and less severe
2. Vector: culex
3. Reservoir: wild birds

Question 6

ARTHROPOD BORNE
1. GENUS OTHOBUNYA VIRUS
A. California Encephalitis Virus complex
vector: __________
Principal vertebrae hosts: small mammals like squirrels, chipmunks, rabbit

Answer 6

Vector: Aedes triseriatus

Question 7

GENUS PHLEBOVIRUS
A. SANDFLY FEVER

1. Vector: P_______–
2. small itching papules on skin which leads to headache, malaise, fever, PHOTOPHOBIA, STIFFNECK

Answer 7

PHLEBOTOMUS

Question 8

GENUS PHLEBOVIRUS
Zoonotic
Mild febrile illness
Vector and reservoir: A mosquito

Answer 8

Aedes

Question 9

RODENT BORNE HEMORRHAGIC FEVER
Zoonotic
MOT: inhalation of ___________ excreta

A. ________ with renal syndrome
- seoul virus
- interstitial nephritis
- generalized hemorrhage and shock
- urban rats persistently infected

Answer 9

1. INHALATION OF RODENT EXCRETA

Question 10

RODENT BORNE HEMORRHAGIC FEVER
HANTAANVIRUS

_____________ SYNDROME
rapidly progress edema; deer mouse is the primary rodent reservoir

Answer 10

Hantavirus pulmonary syndrome