Uworld > Test 93: Incorrect > Flashcards

Test 93: Incorrect Flashcards

(74 cards)

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1
Q

Where does HSV-2 located

A

Sacral dorsal root ganglia

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2
Q

Locomotor ataxia refers to

A

tabes dorsalis

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3
Q

What is postherpetic neuralgia? what is it seen in

A
  • persistent pain after resolution of lesions

- Varicella zoster

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4
Q

name 3 things Sertoli cells secrete

A
  1. inhibin B
  2. androgen-binding protein
  3. MIF (Mullerian inhibitory factor)
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5
Q

Damage to the infraorbital nerve causes what

A
  • paresthesia of upper cheek, upper lip, upper gingiva

- inferior rectus muscle becomes entrapped

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6
Q

Corneal reflex involves what nerves

A
  • cranial nerve V1 sensory

- VII motor nerve

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7
Q

trauma to the superior orbital fissure can cause

A

impaired corneal reflex

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8
Q

Epithelium of ovary

A

simple cuboidal epithelium

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9
Q

Drug of choice for paroxysmal supra ventricular tachycardia

A

adenosine

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10
Q

half life of adenosine

A

less than 10 seconds

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11
Q

side effects for adenosine

A
  • chest burning

- flushing

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12
Q

Another name for cross-sectional study

A

prevalence study

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13
Q

An instruction to leave the bedroom if unable to fall asleep is an example of what therapy for insomnia

A

stimulus control therapy

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14
Q

MOA of Niacin

A
  • decreases hepatic synthesis of triglycerides and VLDL

- reduces clearance of HDL

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15
Q

Side effects of Niacin

A
  • gout
  • flushing
  • hyperglycemia
  • hepatotoxicity
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16
Q

how does orotic acuduria present

A
  • failure to thrive
  • developmental delay
  • megaloblastic anemia refractory to folate and B12
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17
Q

Pyridoxine is supplemented with what drug

A

Isoniazid

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18
Q

S1 nerve root compression causes

A
  • pain/sensory loss down posterior thigh and calf to lateral aspect of foot
  • weakness on thigh extension, knee flexion, and foot plantar flexion
  • absent ankle jerk reflex
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19
Q

L2 or L3 radiculopathy

A
  • paid down anterior thigh

- weakness of hip flexion

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20
Q

L4 radiculopathy

A
  • pain/paresthesia down anterior thigh to medial lower leg and foot
  • no Knee reflex
  • weakness on knee extension
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21
Q

What is the most important mediator of coronary vascular dilation in large and pre-arteriolar vessels

A

Nitric oxide

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22
Q

How much does the nervous system impact the coronary blood flow

A

not much

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23
Q

define splitting

A

seeing all good or all bad

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24
Q

what disorder is splitting seen in

A

borderline

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25
Why does gout occur with increased frequency in pains with activating mutations involving phosphoribosyl pyrophosphate synthetase
- increase production and degradation of purines
26
First-line therapy of acute gout
NSAIDS
27
2nd line therapy for acute gout
Colchicine
28
What is phospholipid composition of the viral particle surface that is highly similar to that of the cell membrane
CMV
29
A virus with a phospholipid-containing particle surface is a virus with what
enveloped
30
Genrally, enveloped viruses acquire their envelopes from where? exception
- plasma membrane | - Herpesvirus: get from nuclear membrane
31
what therapy during pregnancy reduces the risk of perinatal transmission of HIV and is recommended for all pregnant women with HIV
antiretroviral therapy (enzyme inhibitor drug)
32
Oral thrush, interstitial pneumonia, and severe lymphopenia during the first year of life are consistent with what
mother to child vertical transmission of HIV -1
33
What helps down-regulate gastric secretion after a meal the most
intestinal influences
34
femoral nerve arises from what nerve roots
L2-L4
35
Sensory for Iliohypogastric nerve
- suprapubic and gluteal regions
36
motor for iliohypogastric nerve
anterolateral abdominal wall muscles
37
Wallerian degenertaion
axonal degeneration and breakdown of myelin sheath that occurs distal to a site of injury
38
Why does axonal regeneration not occur in CNs
- myelin debri - secretion of neuronal inhibitory factors - development of dense glial scarring
39
How long can myelin debris hang out in the CNS
for years
40
Where is tennis elbow
lateral epicondylitis
41
tennis elbow is what muscle
- extensor carpi radialis brevis
42
job of extensor carpi radials braves
wrist extension
43
Role of interposes muscles
adduction of fingers
44
what virus am I? fever for 3-5 days followed by truncal rash
Herves 6
45
What is wrong in leukocyte adhesion deficiency
- defect in LFA-1 integrin (CD18) protein | - impaired migration and chemotaxis
46
Protective factors for epithelial ovarian cancer
- oral contraceptives - multiparity, breastfeading - tubual ligation
47
risk factors for epithelial ovarian cancer
- infertility - BRACA1 - postmenopausal age
48
What is protein marker for epithelial ovarian cancer
- CA125
49
Muddy brown casts are pathognominic for what
acute tubular necrosis
50
Tinnitus, vertigo and sensorineural hearing loss
Miner disease
51
what is the pathogenesis of Meniere disease
- increase volume and pressure of endolymph in the vestibular apparatus
52
Difference between acoustic neuroma and Meniere disease
Meniere: episodic Neuroma: constant
53
MOA for aminoglycosides
interfering with 30 ribosomal subunit
54
MOA for Quinolones
mutated DNA gyrase
55
single sarcomere is defined as
distance between 2 Z lines
56
I band, what does it touch
actin filaments | - Z lines
57
A band, what line does it touch
think filaments | - M lines
58
Fragile X syndrome occurs when
meiosis of oocytes
59
what does the CGG tirnucleotide repeat cause for Fragile X
- FMR1 hypermethylation
60
Defect in DNA mismatch repair gene causes what syndrome
Lynch syndrome
61
what is lynch syndrome
- increase risk of hereditary non-polyposis colorectal cancer - extraintestinal malignancies
62
Commonly associated rugs with DRESS syndrome
1. Anticonvulsants | 2. allopurinol
63
Lab studies for DRESS will show
eosiniophlia
64
what are clinical manifestations for DESS
- fever - generalized lymphadenopathy - facial edema
65
Which polio virus drug produces a stronger mucosal secretory IgA immune response
live attenuated oral ( Sabin)
66
Fetal growth, retardation, hypertonia ( clenched hands with overlapping fingers), rocker bottom feet, and cardiac/GI/renal effects
Edwards syndrome | trisomy 18
67
what is 5p deletion
Cri-du-chat syndrome | - weak or cat like cry
68
pneumonic for acute pancreatitis
``` I GET SMASHED Idiopathic Gallstones Ethanool Trauma Steroids Mumps Autoimmune Scorpion sting Hypercalcemia Hypertrigliceridemia ERCP drugs ```
69
Most acute pancreatitis is caused by
gallstones and alcohol
70
Patients who have overdoes of beta blockers should be treated with
glucagon, saline and atropine
71
how does glucagon work on heart cells
- G protein - adenylate cyclase - increase cAMP
72
Patient presents with low-grade fever, anorexia/nausea, dark-colored urine, and right upper quadrant abdominal tenderness is highly suggestive of what
acute viral hepatitis
73
what characterizes hepatocyte apoptosis
- cellular shrinkage | - eosinophilia
74
Beta blockers exacerbate what, and masks what
- exacerbate hypoglycemia | - masks its adrenergic symptoms mediated by norepinephrine and epinephrine
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