UWorld_7.14

Question 1

Hep B associated nephropathy

Answer 1

membranous

Question 2

HIV associated nephropathy

Answer 2

FSGS

Question 3

ACUS pap evaluation

Answer 3

-@ 21-24 ==> repeat pap in 1 yr.
- @ >25 ==> HPV testing
(+) ==> colpo
(-) ==> repeat pap + HPV @ 3yrs

Question 4

Presentation of osler-weber-rendu syndrome

Answer 4

• hereditary telangiectasia
• pulmonary AVMs ==> hemoptysis and RtoL shunt
• recurrent nosebleeds and oral lesions

Question 5

Normal liver span =

Question 6

Rubella presentation

Answer 6

• low-grade fever
• cervical/occipital LAD
• maculopapular rash spreads from cranial-caudal and SPARES palms/soles
• conjuctivitis
• forschheimer spots
• @ adults: arthralgias

Question 7

Common cause of irregular menstrual cycles in teens

Answer 7

-HPA axis immaturity ==> inadequate gonadotropin secretion

Question 8

Management of penile fx

Answer 8

1. retrograde urtherogram to look for urethral injury

2. surgical exploration

Question 9

Causes of hypokalemia

Answer 9

• increased intracellular entry of potassium 2/2 insulin, b-agonists, hematopoiesis
• gi losses
• renal potassium wasting 2/2 hyperaldosteronism, diuretics

Question 10

EBV DNA @ CSF in HIV + pt. ==> dx?

Answer 10

primary CNS lyphoma

Question 11

Presentation of primary CNS lymphoma

Answer 11

• HIV + pt.
• AMS
• solitary, weakly ring-enhancing periventricular mass on MRI
• EBV DNA @ CSF

Question 12

Tatrat-resistant acid phosphate + stain ==> dx?

Answer 12

hairy cell leukemia = B-cell chronic leukemia

Question 13

Conjugated hyperbilirubinemia + predom. elevated alk phos ==> evaluation?

Answer 13

• abdominal imaging

- antimitochondrial antibody

Question 14

Conjugated hyperbilirubinemia + normal LFTs + predom. elevated alk phos ==> ddx?

Answer 14

• cholestasis of pregnancy
• malignancy
• cholangiocarcinoma
• primary biliary cirrhosis
• primary sclerosing cholangitis
• choledocholithiasis

Question 15

Conjugated hyperbilirubinemia + normal LFTs + normal alk phos ==> ddx?

Answer 15

• dubin-johnson syndrome

- rotor’s syndrome

Question 16

Conjugated hyperbilirubinemia + predominantly elevated LFTs ==> ddx?

Answer 16

• viral hepatitis
• autoimmune hepatitis
• toxin/drug-related hepatitis
• hemochromatosis
• ischemic hepatitis
• alcoholic hepatitis

Question 17

cystic hepatic lesion + eggshell calcification ==> dx?

Answer 17

• hydatid cyst
• 2/2 infection with echinococcus granulosus
• dogs = definitive host

Question 18

Management of stroke in sickle cell

Answer 18

exchange transfusion

Question 19

BMI in Anorexia

Question 20

Trastuzumab: MOA, SE

Answer 20

• aka “Herceptin”
• MOA: HER2 receptor blocker
• SE: cardiotoxicity

Question 21

Lesch-Nyan syndrome presentation/cause

Answer 21

• hypoxanthin-guanine phosphoribosyl transferase deficiency

- self-mutilation, neuro dysfxn, gouty arthritis, tophus formation

Question 22

Boy with gout ==> dx?

Answer 22

Lesch-Nyan syndrome

Question 23

Kawasaki dz. presentation

Answer 23

-acute vasculitis @ small/med arteries

-

Question 24

Scarlet fever presentation

Answer 24

• exudative pharyngitis
• **no ocular sx (usually)
• sandpaper rash
• straw. tongue, rash, cervical LAD

Question 25

pityriasis rosea presentation

Answer 25

- pink/brown scaly plaque w/central clearing + colarette of scale - followed by maculopapular rash @ "xmas tree" pattern along skin lines

Question 26

Actinic keratoses presentation

Answer 26

- @ chronically sun-exposed areas - erythematous papules 2/central scale - sandpaper - can be squamous precursor

Question 27

Sx of digoxin toxicity

Answer 27

- GI: anorexia, N/V, abdominal pain | - Neuro: fatigue, confusion, weakness, COLOR vision alterations**