Vit & Trace Elements Flashcards

(57 cards)

1
Q

what vit def causes Night blindness, Bitot spots, keratomalacia

A

Vit A

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2
Q

Vitamin A – main role (2)

A

Vision, epithelial differentiation

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3
Q

what vit def causes Rickets (kids), osteomalacia (adults)

A

vit D

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4
Q

Vitamin D – main role

A

Calcium & phosphate homeostasis

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5
Q

what vit def causes Hemolytic anemia (esp. fat malabsorption)

A

vit e

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6
Q

Vitamin E – main role (2)

A

Antioxidant; protects RBC membranes

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7
Q

what vit def causes Prolonged PT, bleeding

A

Vit k

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8
Q

Vitamin K – main role

A

Activates clotting factors

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9
Q

what vit def causes Beriberi

A

vit B1

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10
Q

Vitamin B1 – main role

A

Energy metabolism (decarboxylation)

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11
Q

what vit def causes Angular stomatitis, cheilosis

A

vit B2

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12
Q

Vitamin B2 – main role

A

Redox reactions (FAD, FMN)

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13
Q

what vit def causes Pellagra (diarrhea, dermatitis, dementia)

A

vit b3

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14
Q

Vitamin B3 – main role

A

NAD / NADP synthesis

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15
Q

what vit def causes Seizures, anemia, dermatitis

A

vit b6

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16
Q

Vitamin B6 – main role

A

Amino acid metabolism

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17
Q

what vit def causes Megaloblastic anemia, neural tube defects

A

folate

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18
Q

Folate – main role

A

DNA synthesis, one-carbon transfer

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19
Q

what vit def causes Megaloblastic anemia + neurologic symptoms

A

vit b12

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20
Q

Vitamin B12 – main role

A

Hematopoiesis, neurologic function

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21
Q

what vit def causes Scurvy

A

vit c

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22
Q

Vitamin C – main role (2)

A

Collagen synthesis, iron absorption

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23
Q

Fat-soluble vitamins

24
Q

Water-soluble vitamins

25
Vitamin D – chemical forms
D₂ (ergocalciferol), D₃ (cholecalciferol)
25
Vitamin A – chemical forms
Retinol, retinal, retinoic acid
26
Vitamin E – active form
α-tocopherol
27
Vitamin K – chemical class
Quinone derivatives
28
Vitamin C – chemical name
Ascorbic acid
29
Vitamin B12 – chemical name
Cyanocobalamin
30
Direct vitamin assay measures
vit conc
31
Indirect vitamin assay measures
biologic effect
32
Fat-soluble vitamin measurement tests
HPLC or LC-MS/MS
33
Vitamin K status test
Prothrombin time (PT)
34
Vitamin B12 indirect markers
↑ Methylmalonic acid (MMA) ↑ Homocysteine
35
Best test for long-term folate status
RBC folate
36
Fat-soluble vitamin absorption requires
bile
37
Fat-soluble vitamin absorption with what
fat
38
Fat-soluble vitamin storage
Liver/adipose (toxicity risk)
39
Water-soluble vitamin absorption
Diffusion or active transport
40
Water-soluble vitamin excretion
renal
41
Iron deficiency causes
Microcytic anemia
42
Iron toxicity causes
Hemochromatosis
43
Copper deficiency
Anemia, neutropenia
44
Copper toxicity causes
Wilsons disease
45
Chromium (Cr³⁺) function
enhances insulin action
46
Chromium (Cr⁶⁺)
Toxic, carcinogenic
47
Lead toxicity causes
↓ IQ in children, anemia
48
Aluminum toxicity causes
Dialysis encephalopathy
49
Arsenic toxicity causes
GI distress, neuropathy
50
Cadmium toxicity causes
Renal damage, weak bones
51
Mercury toxicity causes
Neurotoxicity
52
Trace element collection tube
royal blue top
53
Most common trace element error
contamination
54
Best specimen for lead
whole blood
55
Best specimen for arsenic
Urine
56
Why avoid standard tubes for trace element collection
Rubber stoppers contaminate samples