1
Q
- Acquired aplastic anemia may be caused by
A. benzene or benzene derivatives
B. ionizing radiation and vitamin B12
C. purine or pyrimidine analogues
D. all of the above
A
D. all of the above
2
Q
- The sudden appearance of aplastic anemia or pure red cell aplasia is often caused by
A. a hemolytic process
B. an immune process
C. acute leukemias
D. chronic leukemias
A
B. an immune process
3
Q
- Aplastic anemia can occur years before a diagnosis of _____ is made.
A. paroxysmal nocturnal hemoglobinuria
B. myelodysplasia
C. acute myelogenous leukemia
D. all of the above
A
D. all of the above
4
Q
- If a patient with aplastic anemia is referred to as exhibiting pancytopenia, which cell lines are affected?
A. Erythrocytes
B. Leukocytes
C. Thrombocytes
D. All of the above
A
D. All of the above
5
Q
- A characteristic of Fanconi’s anemia is
A. a subset of Fanconi’s anemia
B. a rare congenital form of red cell aplasia
C. is characterized by selective failure of red blood cell production
D. the best-described congenital form of aplastic anemia
A
D. the best-described congenital form of aplastic anemia
6
Q
- A characteristic of familial aplastic anemia is
A. a subset of Fanconi’s anemia
B. a rare congenital form of red cell aplasia
C. is characterized by selective failure of red blood cell production
D. the best-described congenital form of aplastic anemia
A
A. a subset of Fanconi’s anemia
7
Q
- A characteristic of pure red cell anemia is
A. a subset of Fanconi’s anemia
B. a rare congenital form of red cell aplasia
C. is characterized by selective failure of red blood cell production
D. the best-described congenital form of aplastic anemia
A
C. is characterized by selective failure of red blood cell production
8
Q
- A characteristic of Diamond-Blackfan syndrome is
A. a subset of Fanconi’s anemia
B. a rare congenital form of red cell aplasia
C. Is characterized by selective failure of red blood cell production
D. the best-described congenital form of aplastic anemia
A
B. a rare congenital form of red cell aplasia
9
Q
- Fanconi’s anemia is associated with abnormal genes located on chromosomes __q___, __q___.
A. 9, 20
B. 5, 22
C. 9, 12
D. 8, 23
A
A. 9, 20
10
Q
- Acute (transient) red cell aplasia can be associated with
A. a recent viral infection
B. a bacterial infection
C. a parasitic infection
D. idiopathic causes
A
A. a recent viral infection
11
Q
- Diamond-Blackfan anemia (DBA) is a
A. microcytic, hypochromic anemia
B. megaloblastic anemia
C. congenital form of aplastic anemia
D. white blood cell deficiency
A
C. congenital form of aplastic anemia
12
Q
Congenital amegakaryocytic thrombocytopenia is manifested
A. in infancy
B. at about 10 years of age
C. in adolescence
D. in adulthood
A
A. in infancy
