22

Question 1

1. The most common form of chronic leukemia in Western countries
   is
   A. myelogenous
   B. lymphocytic
   C. monocytic
   D. eosinophilic

Answer 1

B. lymphocytic

Question 2

2. The median survival time of patients with CLL, compared with patients with chronic monocytic leukemia, is
   A. not significantly different
   B. shorter
   C. longer
   D. shorter, if the patient is female

Answer 2

C. longer

Question 3

3. CLL is classically a
   A. T-cell disorder
   B. B-cell disorder
   C. null cell disorder
   D. disorder of the young

Answer 3

B. B-cell disorder

Question 4

4. CLL symptoms frequently include
   A. weight loss, anemia, and extreme leukocytosis
   B. absolute lymphocytosis, edema, and splenic infarction
   C. absolute lymphocytosis, malaise, and low-grade fever
   D. neutrophilia, splenomegaly, and anemia

Answer 4

C. absolute lymphocytosis, malaise, and low-grade fever

Question 5

5. Characteristics of malignant lymphoma typically include
   A. overproliferation of neutrophils
   B. overproliferation of lymphocytes
   C. lymph node involvement
   D. both B and C

Answer 5

D. both B and C

Question 6

Hodgkin disease
A. is characterized by neutrophilia in the early stages of the disease
B. occurs more frequently in females than males
C. is a lymphoma, characterized by Reed-Sternberg cells, and occurs more frequently in females than in males
D. is a lymphoma, characterized by Reed-Sternberg cells, and occurs more frequently in males than in females

Answer 6

D. is a lymphoma, characterized by Reed-Sternberg cells, and occurs more frequently in males than in females

Question 7

Rare forms of lymphoma include
A. Hodgkin and non-Hodgkin lymphoma
B. Sézary syndrome and mycosis fungoides
C. Hodgkin and Burkitt’s lymphoma
D. Non-Hodgkin lymphoma and mycosis fungoides

Answer 7

B. Sézary syndrome and mycosis fungoides

Question 8

8. Multiple myeloma is a disorder of
   A. T lymphocytes
   B. megakaryocytes
   C. plasma cells
   D. the lymph nodes

Answer 8

C. plasma cells

Question 9

9. The abnormal protein frequently found in the urine of persons with multiple myeloma is
   A. albumin
   B. globulin
   C. IgG
   D. Bence Jones

Answer 9

D. Bence Jones

Question 10

10. WM is characterized by increased levels of
    A. IgG
    B. IgM
    C. IgD
    D. IgA

Answer 10

B. IgM

Question 11

Which cluster designations are positive in typical HCL?
A. CD25 CD11c, CD19, CD20
B. CD25 CD11c, CD19, CD10
C. CD25 CD11c, CD10, CD5
D. CD25 CD22, CD19, CD20

Answer 11

D. CD25 CD22, CD19, CD20

Question 12

If a 65-year-old female with swollen lymph nodes has a CBC performed and many smudge cells were noted along with lymphocytosis, a probably diagnosis might be
A. chronic lymphocytic leukemia
B. multiple myeloma
C. Hodgkin disease
D. Mantle cell lymphoma

Answer 12

A. chronic lymphocytic leukemia

Question 13

The most common lymphoma in young adults is
A. follicular lymphoma B. mycosis fungoides
C. Hodgkin lymphoma
D. diffuse large B-cell lymphoma

Answer 13

C. Hodgkin lymphoma

Question 14

MGUS is characterized by _________.
A. monoclonal immunoglobulin in a patient’s serum in the presence of a solitary mass of plasma cells
B. significant infiltration of the bone marrow with plasma cells but only a few clinical symptoms of multiple myeloma
C. monoclonal immunoglobulin in a patient’s serum with only a small percentage of infiltration of bone marrow with plasma cells
D. significant infiltration of the bone marrow with plasma cells and monoclonal immunoglobulin in both the patient’s serum and urine

Answer 14

C. monoclonal immunoglobulin in a patient’s serum with only a small percentage of infiltration of bone marrow with plasma cells