9. DIC Flashcards

(8 cards)

1
Q

(DIC)

häufigste Ätiologien

A
  1. Sepsis
  2. Trauma
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2
Q

(DIC)

Pathophysiologie

A
  • systemische Gerinnungsaktivierung
  • gestörte Antikoagulation
  • gestörte Fibrinolyse
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3
Q

(DIC)

Typen

A
  • Typ 1: DIC mit Blutung
  • Typ 2: DIC mit Organversagen
  • Typ 3: DIC mit massiver Blutung
  • Typ 4: asymptomatische DIC
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4
Q

(DIC)

Phänotypen: Folgen
(Beispiel)

A
  • thrombotischer: Organversagen
    (Sepsis)
  • fibrinolytischer: Blutungen
    (hämatologische Erkrankungen)
  • balancierter: asymptomatisch
    (solide Tumoren)
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5
Q

(DIC)

häufigste Organversagen

A
  • ARDS
  • ANV
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6
Q

(DIC)

Diagnostik
(Auswertung)

A

DIC-Score der ISTH

(≥ 5 = manifeste DIC wahrscheinlich)

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7
Q

(DIC)

Score: Parameter

A

DIC-SCORE DER ISTH

Thrombozytenzahl (10^4)
- (1): < 10
- (2): < 5

Quick-Wert
- (1): < 70
- (2): < 50

Fibrinogen
- (1): < 100

Fibrin(ogen)-Spaltprodukte / lösliches Fibrin / D-Dimere
- (2): moderater Anstieg
- (3): starker Anstieg

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8
Q

(DIC)

Therapien
(Indikationen)

A
  • Antikoagulations-
    (bei thrombotischem Typ)
  • Substitutions-
    (bei fibrinolytischem Typ)
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