most common skin problem
acne vulgaris (preadolescent stage)
whitehead, blackhead (exposed)
blackhead (it is oxidized
a sebaceous follicle that is osbtructed
microcomedone
which contains pus (papules or pustules)
PUSTules
main factors of acne
follicular hyperkeratinization, incr sebum production, cutibacterium acnes, inflammation
differentiate moderate and severe acne
severe- with scarring and cysts, moderate- comedones, papules, pustules, nodules
first line for mild acne vulgaris
benzoyl peroxide, or retinoids (or combination), BPO and clinda or BPO and adapalene
when can you see the improvement after using BPO for MILD
after two to three months
first line for moderate acne vulgaris
BPO/retinoids (combina), or BPO +clinda or BPO + adapane PLUS COC or oral antibiotics
first line of SEVERE acne vulgaris
oral isotretinoin (if contra use BPO+retinoid OR COC
oral isotretinoin – lab tests required
preg test, LFT, CBC, cholesterol, COC + USE BARRIER method
SE of tretinoin
peeling, scarring, dryness (use SUNSCREEN)
when to use birth control, 2 forms of birth control even
1 month before, and 1 month after
mmost powerful anti acne
isotretinoin
oral agents for acne
tetra/doxy, COC, and SPIRONO (antiandrogen)
COC SE
VTE
SPIRO SE
hyperkalem, irregular menses, breast tender, fatigue
avoid concurrent use with systemic retinoids
retinoids with tetracyl/doxycyl (risk of htn intracranial)
erythnromycin in pregnancy
erythromycin ESTOLATE (never in preg), other eyrhtomycin- allowed in preg
breastfeeding
allowed tretinoin
what to do in moderate / severe acne
start oral tetra
seeing improbement in acne while using COC but with mood changes, what to do
change to a diff COC