IBS

Question 1

IBS-constipation

Answer 1

Linaclotide (peptide)

Question 2

poor evidence to ibs-constipation

Answer 2

osmotic laxatives, prucalopride (sert agonist)

Question 3

ibs-diarrhea

Answer 3

eluxadoline (opiod receptor modulator)

Question 4

ibs- general (strongly recommended)

Answer 4

TCA- amitriptylline, desipramine, doxepin, imipramine, trimipramine

Question 5

conditionally recommended for ibs-general, bleeding, and QT prolongation

Answer 5

ssri- citalopram, fluoxetine, paroxetine

Question 6

use if failed other treatments or use on an as-needed basis

Answer 6

dicyclomine, hyoscine, pinaverium (antispasmodics)

Question 7

ibs-constipation, pregnant

Answer 7

psyllium (first), senna/bisacodyl (short term)