Tuberculosis

Question 1

types of TB

Answer 1

pulmmonary, extrapulmonary (bone, meninges, GI), millary (multiorgan) atypical (CD4 counts)

Question 2

drugs that may cause TB (reactivation)

Answer 2

immunosuppressants (TNF-alpha inh, infliximab)

Question 3

preventive therapy for TB infection

Answer 3

First line: Rifampin x4 months/ INH + Rifapentine x3months

Question 4

alt. preventive therapy for tB

Answer 4

Isoniazis x9 months/6 months, INH + Rifampin x3 months

Question 5

intensive phase 2 months

Answer 5

RIPEx2months (may discontinue Ethambutol)

Question 6

continuation phase

Answer 6

RI/E x4-7 months

Question 7

what is the vaccine

Answer 7

BCG- (not recommended in Canada), live vaccine

Question 9

TB and pregnancy

Answer 9

RIE- OKAY; RI{E- breastfeeding

Question 10

SE of isoniazid

Answer 10

peripheral neuropathy

Question 11

to be given with INH

Answer 11

vitamin B6- pyridoxine

Question 12

Rifampicin is what in enzyme

Answer 12

ENZYME INDUCER

Question 14

monitor for hepatotoxicity

Answer 14

INH, PYRAZINAMIDE

Question 15

orange body fluids

Answer 15

Rifampin

Question 16

rash, SJS,

Answer 16

ethambutol

Question 17

optic neuritis

Answer 17

Ethambbutol

Question 18

retrobulbar neuritis (how they see red and green)- should be discontinued

Answer 18

Ethambutol