adults
x-rays
downs syndrome
group of disorder manifesting in marrow failure
chemotherapy
radiotherapy
tissue infiltration
Marrow failure
hepatosplenomegaly
gum hypertrophy
there is CNS involvement in ALL and it is very rare in AML
Auer rods
bone marrow biopsy
Platelets RBCs Eosinophils Basophils Neutrophils Monocytes
tumour lysis syndrome
Daunorubicin
Cytarabine
total destruction of leukaemic cells
good (60% = long term)
T
Acute promyelocytic leukaemia
Release of thromboplastin
few
ALL
10%
infection (pancytopenia)
bleeding
acute leukaemias
pancytopenia