[CLL] Flashcards by Johannes Staufenberg

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Mature B cells

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No programmed cell death. Stuck in G0/G1

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Rai stage

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rubbery non tender lymph nodes

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asymptomatic often

weight loss/sweats if severe

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Autoimmune haemolysis
Infection
Marrow failure

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hypogammaglobulinaemia (IgG low)

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herpes zoster

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raised in serum

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low

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Low

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low

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T

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Fludarabine
Cyclophosphamide
rituximab

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Symptomatic
unmutated Ig genes
17p deletions

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Q

Study These Flashcards

A

17p (e.g. del17p13)

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Radiotherapy

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Pneumonia

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yes

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Steroids