What are the three main nutrient types?
Growth, maintenance, repair
What do carbs provide?
Glucose
What do proteins provide?
Amino acids
What do fats/oils provide?
Fatty acids
What is the role of liver cells?
Convert one type of food molecule to another
What is the major fuel of the cell?
Glucose
Respiration equation
C6H12O6 + 6O2 ->6CO2 + 6H2O
ADP+Pi ->ATP
How is excess glucose stored?
Chemical reactions
Provide energy needed to maintain homeostasis
Perform essential functions
What is catabolism?
Large to small
Energy released
What is anabolism?
Small to large
Energy used
The molecules formed by anabolism:
What are the three stages of oxidation of glucose to produce ATP?
1) Glycolysis - in the cytoplasm - with or without oxygen = anaerobic
2) Krebs cycle aka citric acid cycle
3) ETC - both in the mitochondria - require oxygen = aerobic
Carbs are catabolised into
Glucose
Fats are catabolised into
Fatty acids and glycerol
Proteins are catabolised into
Amino acids
Glucose, fatty acids and glycerol and amino acids can enter the krebs cycle…
Releasing energy and Co2
Gluconeogenesis:
Glucose created from non-carb carbon sources, to maintain blood glucose levels during fasting or other periods of low carb availability
krebs cycle -> Pyruvate + glycerol + lactic acids + fatty acids + amino acids (60%) -> Glucose
Carbohydrate (glucose) catabolism equation
Amino acids from protein breakdown
+
fatty acids liberated from adipose tissue
+
pyruvate from glycolysis
+
oxygen from haemoglobin in blood or from muscle cells
=
34/36 ATP
3436 ATP + H2O + CO2 + Heat
Glycolysis
Breaking glucose
Occurs in cytosol
Anaerobic
Pyruvate can enter 2 pathways
2 minutes of energy
(2ATP released)
Krebs cycle
Repeating sequence of reactions
Occurs in mitochondria
Anaerobic
One CO2 removed from pyruvate
leaving acetyl group to be picked to -> acetyl CoA
ETC
Series of electron transporters embedded in the inner mitochondrial membrane that shuttles electrons from NADH and DADH2 to molecular oxygen
Increased loss of nutrients caused by
Malabsorptions
Diarrhoea
Glycosuria
Haemorrhage
Reduced nutrient intake caused by
Nausea
Anorexia
Poverty
Pain
Dysphagia