Cerebrospinal Fluid

Question 1

CSF

Answer 1

Fluid which circulates in ventricles and central canals of CNS also fills subarachnoid space and cisterns

Question 2

Production

Answer 2

Secreted by choroid plexuses in brain ventricles

Question 3

Choroid plexuses in ventricle sites

Answer 3

1. One in central part floor of each lateral ventricle
2. One in inferior horn medial wall of each lateral ventricle
3. Pair in roof of each of 3rd and 4th ventricle

Question 4

Circulation

Answer 4

It circulates in CNS ventricles and central canals

Question 5

Drainage

Answer 5

After circulation:
1. It drains out from 4th ventricle through 3 apertures found in roof reaching subarachnoid space:
- 1 median
- 2 lateral
2. It then flows over brain and spinal cord surfaces

Question 6

Absorption

Answer 6

CSF finally leaves subarachnoid space by means of arachnoid villi and granulations to drain in Dural venous sinuses

Question 7

Functions

Answer 7

1. Takes lymph place in CNS which is devoid of lymph vessels
2. Acts as protective water cushion in subarachnoid space, it protects the brain and spinal cord and minimize shock effects
3. Intracranial pressure regulation
4. Reduces brain weight 30 folds

Question 8

Amount

Answer 8

Average amount in adults is about 135cc
It is constantly absorbed and produced in rate of 400-500cc daily (renewed 3 times daily)

Question 9

Pressure

Answer 9

Normally about 100mm in water

Question 10

Obstruction leads to

Answer 10

Obstruction to its normal passage especially at narrow foramina and canal causes:
1. Increased intracranial pressure
2. Ventricles dilatation (hydrocephalus)